Unilateral adrenal histoplasmosis

Khaled, Dunia; Gills, J.P.

doi:10.1016/j.eucr.2018.03.010

Cited by 3 publications

(1 citation statement)

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“… 9 This mechanism for fungal dissemination allows for infection of various organ systems, the most common of which is the adrenal glands. 10 , 11 This progressive dissemination occurs when the immune system is unable to formulate a sufficient T-cell-mediated response to clear the yeast from the human body Patients are often unaware of contracting the fungus, given that the majority of cases are asymptomatic. 8 Nonetheless, symptomatic HP has 3 forms of presentation: acute primary HP, chronic cavitary HP, and progressive disseminated HP.…”

Section: Discussionmentioning

confidence: 99%

A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge

Govindarajan

Sous

Venter

et al. 2023

Journal of Investigative Medicine High Impact Case Reports

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Histoplasma capsulatum is a geographically specific dimorphic fungus that can cause a spectrum of diseases. While most cases are asymptomatic pulmonary infections, in severe cases, particularly in immunocompromised patients, disseminated disease can occur. Histoplasmosis in California is limited to only a few case reports. In this article, we describe a rare case of disseminated histoplasmosis in a non-endemic region presenting with diagnostically challenging symptomatology, including altered mental status, status epilepticus, septic shock, and bilateral adrenal masses.

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