Uniformly-sized, molecularly imprinted polymers for (−)-epigallocatechin gallate, -epicatechin gallate and -gallocatechin gallate by multi-step swelling and polymerization method

Separation of Epigallocatechin Gallate from Natural Plant Extracts Using Crowding Agents—Assisted Imprinted Polymers

“…2c). The ratio is comparable with the result by Haginaka et al for the imprinting of EGCG with 2-VP [19]. The result suggested that high levels of crosslinker might lead to the stiffness of the polymer network increasing severely, thus decreasing the accessibility of the cavities significantly.…”

“…To date, a number of EGCGimprinted polymers have been made using bulk polymerization but lower imprinting factors (1.3-3.22) [17,18]. A greater imprinting factor (11) can be obtained by a multistep swelling method [19], but the method is too tedious. Thus, developing a simple and highly selective method to imprint EGCG is necessary.…”

Strategies in the Analysis of Plant Flavonoids

“…Recently, an MIP showing good binding affinity toward quercetin, catechin, and epigallocatechin gallate has been prepared using quercetin as template and 4-vinylpyridine as functional monomer (Castro-López et al, 2012). There are also examples in the literature describing the preparation of different types of MIPs for selective extraction of catechins, which, in general, showed high molecular recognition ability for the respective template molecule (e.g., epicatechin, epigallocatechin, epicatechin gallate, or epigallocatechin gallate), although the competitive adsorption of other catechins was usually observed (Blahova, Lehotay, and Skacani, 2004;Ding et al, 2006;Haginaka et al, 2007). Other molecularly imprinted materials developed for the extraction of flavonoids have used template molecules such as the flavone luteoline for the preparation molecularly imprinted silica microspheres (Zhang, Qin, and Tu, 2007), or the flavanone naringin using β-cyclodextrine (Ma et al, 2011) or acrylamide (Tasselli, Donato, and Drioli, 2008) as functional monomers.…”

Molecularly imprinted polymer microspheres for solid‐phase extraction of protocatechuic acid in Rhizoma homalomenae

“…To date, many MIPs are still made using the conventional bulk polymerization method. The prepared MIP materials have irregular shape due to a low yield, time-consuming, crush and sieve process, but these problems have been solved by using suspension polymerization [4], swelling polymerization [5], grafting procedures [6] and precipitation polymerization [7]. Precipitation technique, which has been used to deliver spherical imprinted particles in a single preparative step without adding stabilizers to the reaction system, is a particularly convenient method for MIP synthesis, and is applied to prepare imprinted spheres for a variety of different analytes and applications [8].…”