Unieke gedragsfenotipes in die hertmuismodel (deer mouse model) van obsessiewe-kompulsiewe siekte en die reaksie daarvan op serotonergiese en dopamienergiese geneesmiddelbehandeling
Abstract:Slegs 40 tot 60% van pasiënte met obsessiewe-kompulsiewe siekte (OKS) reageer voldoende op eerstelinie-selektiewe serotonienheropnameremmers (SSHRs). Wat egter selfs belangriker is, is dat slegs sowat die helfte van SSHR-weerstandige pasiënte wat vervolgens aanvullende behandeling ontvang, positief daarop reageer.
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