Unidirectional valve patch for repair of cardiac septal defects with pulmonary hypertension

The unidirectional valve patch provides no benefits to early and long-term survival in patients with ventricular septal defect and severe pulmonary artery hypertension

“…12,13 The UVP was also described by Ad and associates, 14 who adopted a 1-way, valved, atrial septal patch in 18 patients. Then Zhou and coworkers 15 adopted a similar UVP in the treatment of VSD complicated with Eisenmenger syndrome, and Zhang and colleagues 16 developed a unidirectional monovalve homologous aortic patch for repair of VSD with PAH. Novick and associates 17 reported the use of a nonfenestrated patch closure for children younger than 6 years with severe PAH, but the operative mortality was very high.…”

“…The VSD was closed by means of a standard procedure with a Dacron patch in the NVP group, whereas a UVP was used to close the VSD in the UVP group, as previously described. 2 In brief, the UVP was constructed from a Dacron patch approximately as large as the defect to be closed. A hole approximately 0.5 to 1.0 cm in diameter was made in the patch somewhat off center.…”

Unidirectional valved patches for closure of septal defects in patients with severe pulmonary hypertension

“…Two deaths in Zhou's experience[17] were during the learning curve. One patient died due to acute right ventricular failure and another due to respiratory failure.…”

“…[17–21] The principles of all these techniques essentially remain the same. These patches are designed to function like the fossa ovalis of the atrial septum.…”

“…In 1995, Zhou et al .,[17] first described UVP for closure of ventricular septal defects (VSD) in patients with severe PAH [Figure 2]. The UVP was constructed from a Dacron patch approximately as large as the size of the defect to be closed.…”