Unidirectional large-amplitude oscillatory shear flow of human blood

Saengow, Chaimongkol; Giacomin, A. Jeffrey; Dimitrov, Andrea Stephanie

doi:10.1063/1.5127868

Cited by 21 publications

(15 citation statements)

References 59 publications

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“…(5) to its special case, the corotational Jeffreys (CJ) fluid. This special case has proven to explain the shear stress response of human blood sufficiently in udLAOS [12].…”

Section: Exact Normal Stress Differencesmentioning

confidence: 89%

“…1 of Ref. [12]). The flow is generated by superposing large-amplitude oscillatory shear flow (LAOS) onto steady shear flow.…”

Section: Introductionmentioning

confidence: 88%

“…2, and then nondimensionlizing the result Retardation time Following Ref. [12], we use ŵ to indicate dimensionless quantities. For the CJ fluid, we next set…”

Section: Exact Normal Stress Differencesmentioning

confidence: 99%

“…To investigate hemorheology, some use blood biochemistry and microstructures to model blood [17][18][19][20][21][22]. These molecular models can provide direct insights, but computational cost is generally [23]; [12,24]). Furthermore, it has been tested in several material systems, including molten polymers and polymer solutions [23,25,26], wormlike micelles [27], and human blood [12].…”

Section: Introductionmentioning

confidence: 99%

“…These molecular models can provide direct insights, but computational cost is generally [23]; [12,24]). Furthermore, it has been tested in several material systems, including molten polymers and polymer solutions [23,25,26], wormlike micelles [27], and human blood [12]. This framework is given by Eq.…”

Section: Introductionmentioning

confidence: 99%

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Normal Stress Differences of Human Blood in Unidirectional Large-Amplitude Oscillatory Shear Flow

Saengow

Giacomin

Dimitrov

2020

Journal of Fluids Engineering

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This work analyzes normal stress difference responses in blood tested in unidirectional large-amplitude oscillatory shear flow (udLAOS), a novel rheological test, designed for human blood. udLAOS mimics the pulsatile flow in veins and arteries, in the sense that it never reverses, and yet also nearly stops once per heartbeat. As for our continuum fluid model, we choose the Oldroyd 8-constant framework for its rich diversity of popular constitutive equations, including the corotational Jeffreys fluid. This work arrives at exact solutions for normal stress differences from the corotational Jeffreys fluid in udLAOS. More generally, predictions from the Oldroyd 8-constant framework are explored by means of the finite difference method. Finally, the generalized versions of both the Oldroyd 8-constant framework and the corotational Jeffreys fluid are employed to predict the nonlinear normal stress responses the model parameters fitted to udLAOS measurements from three very different donors, all healthy. From our predictions, we are led to expect less variation in normal stress differences in udLAOS from healthy donor to donor, than for the corresponding measured shear stress responses.

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“…(5) to its special case, the corotational Jeffreys (CJ) fluid. This special case has proven to explain the shear stress response of human blood sufficiently in udLAOS [12].…”

Section: Exact Normal Stress Differencesmentioning

confidence: 89%

“…1 of Ref. [12]). The flow is generated by superposing large-amplitude oscillatory shear flow (LAOS) onto steady shear flow.…”

Section: Introductionmentioning

confidence: 88%

“…2, and then nondimensionlizing the result Retardation time Following Ref. [12], we use ŵ to indicate dimensionless quantities. For the CJ fluid, we next set…”

Section: Exact Normal Stress Differencesmentioning

confidence: 99%