Unicystic ameloblastoma

Pattipati, Sreenivasulu; Ramaswamy, P; Kumar, B. Praveen; Khaitan, Tanya

doi:10.1007/s12548-012-0067-2

Cited by 2 publications

(3 citation statements)

References 10 publications

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“…Although UA is a variant of ameloblastoma, it is considered to have a relatively benign biological behavior and a better response to conservative treatment, resulting in a better prognosis. [ 2 , 3 , 13 – 15 ] UA is believed to be less aggressive than ameloblastomas and to respond more favorably to conservative management, including enucleation, curettage, and marsupialization. [ 15 , 16 ] Marsupialization is reported to be a more effective treatment for cystic lesions than other treatments.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 , 3 , 13 – 15 ] UA is believed to be less aggressive than ameloblastomas and to respond more favorably to conservative management, including enucleation, curettage, and marsupialization. [ 15 , 16 ] Marsupialization is reported to be a more effective treatment for cystic lesions than other treatments. Nakamura et al [ 11 ] reported a series of 24 UAs treated with marsupialization, among which 16 lesions regressed to less than half their initial size.…”

Section: Discussionmentioning

confidence: 99%

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Expression of TP53 and IL-1α in unicystic ameloblastoma predicts the efficacy of marsupialization treatment

et al. 2018

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In this study, we evaluated the effects of marsupialization in treating unicystic ameloblastoma (UA) and investigated the relationship between TP53 and interleukin 1 α (IL-1α) expression and the clinical outcome of UA treated with marsupialization.Consecutive patients treated with marsupialization and curettage at Shanghai Ninth People's Hospital were included. According to the unified standard, 48 patients were included in this study. Of these, 20 showed a good response, 10 a partial response, and 18 no response, based on the outcome of the marsupialization procedure. The expression of proteins TP53 and IL-1α was detected with immunohistochemistry (IHC). The clinical and pathological characteristics of the patients were analyzed.Analysis of the clinical and pathological characteristics showed that the effects of marsupialization treatment were significantly associated with lesion location (P < .001) and tumor diameter (P = .01). IHC showed that TP53 expression was significantly higher in the good-response group than in the partial- or no-response group (P = .02), and IL-1α expression was significantly higher in the good-response group than in the partial- and no-response groups (P = .03).Marsupialization is an effective preliminary procedure for treating UA before curettage and peripheral ostectomy. The expression of the TP53 and IL-1α proteins correlates directly with the outcome of UA treated with marsupialization.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Expression of TP53 and IL-1α in unicystic ameloblastoma predicts the efficacy of marsupialization treatment

et al. 2018

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“…Ameloblastomas are thought to represent 1% of all the cysts/tumors of the jaws and 18% of all the odontogenic neoplasms. 1 There are four major clinico-radiographic types: conventional solid or multicystic ameloblastoma, which is the most common type, unicystic, peripheral and desmoplastic variants.…”

Section: Introductionmentioning

confidence: 99%

Unicystic Ameloblastoma Presenting as a Multilocular Radiolucency in the Anterior Mandible: A Case Report

Figueiredo

Meena

Dinkar

et al. 2015

J Dent Res Dent Clin Dent Prospects

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Ameloblastomas are tumors of odontogenic epithelial origin. The term unicystic ameloblastoma is used to describe cystic lesions with clinico-radiographic features resembling an odontogenic cyst, but histologically showing the presence of ameloblastomatous epithelium lining part of the cyst cavity. A large majority of lesions are found in the mandible, and usually cause a painless swelling of the jaws. They can be radiographically subdivided into 'dentigerous' and 'non-dentigerous' types. The unicystic ameloblastoma is believed to be less aggressive than a solid/multicystic ameloblastoma, and thus has a more favorable response to enucleation and curettage. This case report presents a case of unicystic ameloblastoma with a multilocular radiographic appearance in the anterior mandible of a 45-year-old female patient, along with a literature review of the topic.

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Unicystic ameloblastoma

Cited by 2 publications

References 10 publications

Expression of TP53 and IL-1α in unicystic ameloblastoma predicts the efficacy of marsupialization treatment

Expression of TP53 and IL-1α in unicystic ameloblastoma predicts the efficacy of marsupialization treatment

Unicystic Ameloblastoma Presenting as a Multilocular Radiolucency in the Anterior Mandible: A Case Report

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