Unicorns, dragons, polymyositis, and other mythological beasts

119th ENMC international workshop: Trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10–12 October 2003, Naarden, The Netherlands

“…First, the majority of patients in this study would have been diagnosed as PM according to the Bohan and Peter criteria (because of the absence of skin features). In view of the differences in histopathology within this group it is conceivable that this group comprises patients with different immunopathogenesis [23]. This is important if drugs with more specific immunological actions are to be investigated in future RCTs.…”

Immune and myodegenerative pathomechanisms in inclusion body myositis

“…However, it is likely that the prevalence of IBM is still underestimated. Although heavily debated, it is conceivable that a significant number of patients diagnosed with PM might in fact suffer from IBM 35, 36, 37, 38. Aside from erroneous diagnoses, the slowly progressive nature of the disease course and the heterogenicity in its clinical presentation make the condition prone to delayed diagnosis.…”

Diagnostic des myopathies inflammatoires au CHU de Bordeaux de 2012 à 2014

“…Longtemps on a distingué les dermatomyosites (DM) et les polymyosites (PM). Cette classification a été remise en cause par la découverte de nouveaux AAC et le démembrement d'entités spécifiques, la PM « isolée » est devenue rare [3]. Il est désormais consensuel de classer les MI au sein des entités suivantes : dermatomyosites ; myosites de chevauchement [4] classées en trois entités : associées à une connectivite, associées à un AAC non spécifique, syndrome des AS [5] ; PM (définition histologique et absence d'AAC associé ou spécifique) et MNAI [6,7].…”