Unexplained muscle atrophy as the unique preceding symptom of bilateral linear morphea

Localized Scleroderma: MR Findings and Clinical Features

“…In addition, MR imaging was used to detect musculoskeletal involvement in more than one-third of the patients in whom it was not clinically suspected. Although this has to be proved in prospective studies, our data highlight the observations in some case reports and small case series in which authors have proposed the use of MR imaging as an additional tool in the work-up of patients with LS (12)(13)(14)(15)(16)(17)(18)25,26 ). Because longitudinal studies that focus on the clinical course of MR-detected musculoskeletal manifestations are lacking, we cannot determine the importance of these manifestations in terms of prognosis and clinical course.…”

“…Musculoskeletal manifestations should be carefully monitored in patients with LS, and the disease should be treated aggressively (9)(10)(11). The use of magnetic resonance (MR) imaging has been proposed anecdotally for LS (12)(13)(14)(15)(16)(17)(18). To date, MR imaging has only been recommended for the identifi cation of intracerebral alterations in cases of morphea involving the head and neck ( 2,11 ).…”

Diagnostic criteria, severity classification and guidelines of localized scleroderma

“…There has been one case in which functional cerebral hemispherectomy was performed for epilepsia partialis continua, and two cases in which a partial corticectomy was performed for treatment‐resistant epileptic seizures, and the symptoms improved in all cases. There are also reports of cases in which progressive multifocal encephalopathy, stroke and peripheral neuropathy were well controlled with corticosteroids . There was also one case in which steroid pulse therapy effectively treated hemiparesis, and one case in which steroid pulse therapy and high‐dose Ig i.v.…”

“…There are also reports of cases in which progressive multifocal encephalopathy, stroke and peripheral neuropathy were well controlled with corticosteroids. [158][159][160] There was also one case in which steroid pulse therapy effectively treated hemiparesis, and one case in which steroid pulse therapy and high-dose Ig i.v. therapy were reported to be ineffective.…”

Paraspinal and Scapular Myopathy Associated With Scleroderma

“…17 In addition, focal myopathic changes may be found underlying linear scleroderma lesions (morphoea). 17,18 We describe a less well-recognized form of myopathy, which may occur in patients with different types of scleroderma, in which the posterior cervical and lower paraspinal muscles and muscles of the shoulder girdles are particularly affected.…”