Unexpectedly high toxicity of MACOP‐B in young patients with low grade lymphoma

Arranz, Reyes; Gracia, Pérez; Steegmann, Juan Luis; Cámara, Rafael de la; Tomás, J F; Figuera, Á; Vázquez, L; Fernández-Rañada, J M

doi:10.1002/ajh.2830380115

American J Hematol

1991

DOI: 10.1002/ajh.2830380115

|View full text |Cite

Unexpectedly high toxicity of MACOP‐B in young patients with low grade lymphoma

Reyes Arranz

Pérez Gracia

Juan Luis Steegmann

et al.

Abstract: We report the results of treatment with MACOP-B in 11 young patients with low grade lymphoma (LGL). Complete remission was obtained in 4 (57%) and partial remission in 3 (42.8%) of 7 evaluable patients. However, this aggressive chemotherapy has not offered any advantage because of an unacceptably high treatment-related morbidity and mortality (17%). Serious infection during neutropenia was the most common complication.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1996

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 7 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Long-Term Follow-Up After Curative Surgery for Early Gastric Lymphoma

Bartlett¹,

Karpeh²,

Filippa

et al. 1996

Annals of Surgery

View full text Add to dashboard Cite

ObjectiveThis study was designed to examine the long-term survival of a homogenous group of patients with stage IE or IIE-1 gastric lymphoma after complete surgical resection. Summary Background DataThe management of gastric tymphoma remains controversial. Enthusiasm for muftimodality approaches for gastric tymphoma has lead to the current trend of using chemotherapy as primary treatment, thus avoiding gastric resection. Surgery, however, may result in improved long-term survival rates. MethodsThe records of all patients with the diagnosis of gastric lymphoma from 1980 to 1991 were reviewed retrospectively. Of 106 patients examined, 34 underwent curative resection and regional tymphadenectomy for pathologically staged IE or IIE-1 (pN1) gastric tymphoma. Fifteen patients underwent surgery alone, whereas 19 also received postoperative adjuvant therapy. ResultsThe median follow-up time was 74 months. The 10-year actuarial disease-free survival was 91% for stage IE disease (n = 23) and 82% for stage IIE-1 disease (n = 11). There were no operative deaths and a 26% morbidity rate. No difference in survival was found for those treated with adjuvant therapy. ConclusionsThe results compare favorably to those reported with the use of prmary chemotherapy and radiation therapy and suggest that surgery remains the best frontine therapy for early gastric lymphoma.

show abstract

Long-Term Follow-Up After Curative Surgery for Early Gastric Lymphoma

Bartlett¹,

Karpeh²,

Filippa

et al. 1996

Annals of Surgery

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Unexpectedly high toxicity of MACOP‐B in young patients with low grade lymphoma

Cited by 1 publication

References 7 publications

Long-Term Follow-Up After Curative Surgery for Early Gastric Lymphoma

Long-Term Follow-Up After Curative Surgery for Early Gastric Lymphoma

Contact Info

Product

Resources

About