Unexpected diversity and ecological significance of uncultivable large virus-like particles in aquatic environments
Hermine Billard,
Maxime Fuster,
François Enault
et al.
Abstract:The discovery of Jumbo phages and giant viruses of microeukaryotes has transformed our perception of the virosphere. Metagenomic and metatranscriptomic data further highlight their diversity and ecological impact. Nevertheless, sequence-based approaches fail to take into account the morphological diversity of non-cultivated viruses, resulting in our fragmented understanding of their nature and role in the environment. Here, we combined flow cytometry and electron microscopy to uncover both previously unsuspect… Show more
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