A n 84-year-old woman was admitted to our institution for transapical aortic valve implantation (TAVI) because of severe aortic stenosis coexisting with high-risk clinical conditions. She had a past history of type 2 diabetes mellitus, hypertension, intrinsic asthma, moderate to severe chronic renal insufficiency (Modification of Diet in Renal Disease glomerular filtration rate, 36 mL/min per 1.73 m 2 ), and peripheral atherosclerotic vascular disease involving both iliofemoral arteries. Eighteen months before, she had suffered a non-ST-segment elevation myocardial infarction and was treated with 2 bare metal stents on the middle segment of the left anterior descending coronary artery and the very proximal or ostial segment of the right coronary artery. Aortic stenosis was evaluated as moderate. After 5 months, she developed advanced Mobitz II-type atrioventricular block, and a permanent sequential atrial synchronous ventricular inhibited pacemarker was indicated. Progression of the aortic valve disease was not noted. More recently, she was admitted to another hospital with severe dyspnea, showing signs of acute heart failure on physical examination. Urgent transthoracic echocardiogram disclosed a normal left ventricle with preserved ejection fraction and progression of the severity of the aortic valve stenosis. Because of the very high operative risk, conventional on-pump aortic valve replacement was dismissed.Before TAVI, a complete transesophageal echocardiographic (TEE) study confirmed the presumptive diagnosis of severe aortic stenosis (Figure 1). The findings were those expected for degenerative valvulopathy (severe thickness and calcification of the leaflets and critical reduction of the valve opening), showing normal characteristics of the aortic root. Precise measurement of the aortic annulus was accomplished with TEE to determine the appropriate prosthetic size. A successful procedure with a 23-mm SAAPIEN bovine pericardial valve (Edwards Lifesciences Inc, Irvine, Calif) was performed. Intraoperative TEE and fluoroscopy confirmed only minimal aortic regurgitation. The patient was discharged on the 10th postoperative day in very good condition, with normal function of the bioprosthesis on echocardiography. At 3-and 6-month follow-ups, the patient was in functional class II, and the echocardiograms revealed good function of the valve, with minimal aortic regurgitation observed during both checkups.One year later, the patient presented with angina with atypical characteristics. She was referred again to the echocardiography laboratory to assess prosthetic function and coronary stent patency with pharmacological stress. The echocardiogram under basal conditions revealed a pseudoaneurysm in the anterior wall of the aortic root (Figure 2A). Immediate TEE with the use of a 3-dimensional TEE probe (Philips, Andover, Ma) allowed us to better delineate the pseudoaneurysm ( Figure 2B). The pseudoaneurysm caused compression of the main left coronary artery and was therefore responsible for the angina (Figure 3 and...