Une étiologie inhabituelle d’hématurie macroscopique en salle d’urgence : la nécrose papillaire rénale chez le patient drépanocytaire hétérozygote

Verschuren, Franck; Thys, F.; Wa, I. Kong Kam

doi:10.1016/j.jeur.2008.06.004

Cited by 2 publications

(6 citation statements)

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“…In the literature, the cases reported in Europe and in the world were from Africa. For example, with Verschuren, et al in Belgium [3] the patient was 28-years-old and was African. In the study by Guédenon, et al [4] the three patients were respectively 15, 16 and 21-years-old and were from Togo and in the study by Duvic, et al in France [5] the mean age was 26.8 years (17-53 years), the population was made up of six men and four women and out of the 10 patients one from Togo, one from Mauritania, one from…”

Section: Discussionmentioning

confidence: 99%

“…The hematuria reported by the various authors was total and clotting [3]. All patients with sickle cell disease, whether homo or heterozygous, can experience hematuria.…”

Section: Introductionmentioning

confidence: 97%

“…In regions where bilharzia is endemic or hematuria is common, consultation time can be long. According to the authors, the time spent before consultation varies from 2 weeks to 3 years [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

“…All patients with sickle cell disease, whether homo or heterozygous, can experience hematuria. However, the heterozygous AS form is more commonly reported [1,3].…”

Section: Introductionmentioning

confidence: 99%

“…For the rest of the treatment, it is purely symptomatic. It consists of bladder lavage to prevent bladder clotting, blood transfusion [3,4].…”

Section: Introductionmentioning

confidence: 99%

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Int Arch Urol Complic

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Introduction: Hematuria in patient with sickle cell disease (SCD) results from microthrombotic infarction in the vasa recta and peritubular capillaries of the renal medullar, with extravasation of blood in the collecting tubes. Case description: These were 2 patients with heterozygous SCD with highly abundant macroscopic hematuria. The patients were 23 and 31 and had a clotting total hematuria. They were both anemic with good renal function. Cystoscopy had found bleeding from the left kidney in both patients. Uro-tomodensitometry and diagnostic uretero-renoscopy were without particularity for both patients. Treatment consisted of transfusions, oral rehydration, and hydergine for vaso-occlusive crisis. Conclusion: Hematuria in heterozygous sickle cell disease can be massive. In our African regions, this case should be considered after having eliminated urothelium cancer.

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Section: Discussionmentioning

confidence: 99%

“…The hematuria reported by the various authors was total and clotting [3]. All patients with sickle cell disease, whether homo or heterozygous, can experience hematuria.…”

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

“…All patients with sickle cell disease, whether homo or heterozygous, can experience hematuria. However, the heterozygous AS form is more commonly reported [1,3].…”

Section: Introductionmentioning

confidence: 99%

“…For the rest of the treatment, it is purely symptomatic. It consists of bladder lavage to prevent bladder clotting, blood transfusion [3,4].…”

Section: Introductionmentioning

confidence: 99%

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2021

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Hématuries Macroscopiques dans le Service d’UrologieAndrologie du CHU de KARA, Togo : Aspects Épidémiologiques, Cliniques, Étiologiques, et Thérapeutiques

Mbuya,

Sikpa,

Agbedey

et al. 2024

ESJ

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Introduction : L’hématurie macroscopique est un motif fréquent de consultation en urgence dans un service d’urologie. L’objectif de cette étude était d’évaluer les aspects épidémiologiques, cliniques, étiologiques et thérapeutiques des hématuries macroscopiques, dans le service d’Urologie-Andrologie du CHU de KARA. Méthodologie : Il s'est agi d'une étude descriptive transversale, avec une récolte rétrospective des données. Elle avait porté sur 45 patients avec hématurie macroscopique, hospitalisés dans ledit service au cours de la période allant de janvier 2020 à septembre 2023 soit 45 mois. Résultats : La fréquence hospitalière était de 10,5%. Les patients étaient majoritairement de sexe masculin (95,6%) avec un âge moyen de 62,5±16,2 ans. L’hématurie était totale chez 43 cas soit (95,6%). L’hypertrophie bénigne de la prostate était l’étiologie principale retrouvée dans 40% des cas, suivie du cancer de la prostate dans 24,4% des cas, et de la tumeur vésicale dans 15,5% des cas. Le Sondage uretrovesical suivi de l’irrigation ont été réalisés chez 88,9% des patients ; Quinze (15) patients ont été opérés dont 33,3% d’adénomectomie prostatique d’hémostase par voie haute. Aucun décès n’a été enregistré. Conclusion : L’hématurie est une urgence urologique à spectre diagnostique très large allant de pathologies bénignes comme l’infection (cystite hémorragique) ou le calcul à des tumeurs malignes. Elle implique une prise en charge précoce et rigoureuse. Introduction : Macroscopic hematuria is a frequent reason for emergency consultation in a urology department. The objective of this study was to evaluate the epidemiological, clinical, etiological and therapeutic aspects of macroscopic hematuria, in the Urology-Andrology department of KARA University Hospital. Methodology: This was a descriptive, cross-sectional study, with retrospective data collection. It focused on 45 patients with macroscopic hematuria, hospitalized in the said department during the period from January 2020 to September 2023, either 45 months. Results : Hospital frequency was 10.5%. The patients were predominantly male (95.6%) with a mean age of 62.5±16.2 years. Hematuria was total in 43 cases (95.6%). Benign prostatic hypertrophy was the main etiology found in 40% of cases, followed by prostate cancer observed in 24.4% of cases, and bladder tumor in 15.5% of cases. The uretrovesical catheterization followed by irrigation was carried out in 88.9% of patients; Fifteen (15) were operated on, including 33.3% for prostatic adenomectomy for upper hemostasis. No deaths have been recorded. Conclusion : Hematuria is a urological emergency with a very broad diagnostic spectrum ranging from benign pathologies such as infection (hemorrhagic cystitis) or stones to malignant tumors. It involves early and rigorous treatment.

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Une étiologie inhabituelle d’hématurie macroscopique en salle d’urgence : la nécrose papillaire rénale chez le patient drépanocytaire hétérozygote

Cited by 2 publications

References 8 publications

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Hématuries Macroscopiques dans le Service d’UrologieAndrologie du CHU de KARA, Togo : Aspects Épidémiologiques, Cliniques, Étiologiques, et Thérapeutiques

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