Une encéphalite limbique non paranéoplasique révélée par une amnésie antérograde

Lang, Pierre Olivier; Sellal, François

doi:10.1016/j.lpm.2007.11.013

Cited by 1 publication

(1 citation statement)

References 23 publications

(27 reference statements)

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“…The psychic manifestations include behavioural disorders, such as aggression, agitation, irritability, panic attacks and hallucinations. They are associated with neurological manifestations, such as impairment of antegrade memory (100% of cases), epileptic seizures (83.3% of cases), dysautonomia signs (76.7% of cases) and vigilance disorders (66.7% of cases) [41]. Prodromes were found after a thorough examination (33.3% of cases), although few studies were interested in this parameter, which is most commonly seen in anti-NMDAr encephalitis (70% to 86% of cases) [9].…”

Section: Discussionmentioning

confidence: 99%

Dysimmune Encephalitis: Clinical Study

Hakim¹,

Daoudi²

2023

JNNR

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Introduction: Autoimmune encephalitis is a new and little-known entity targeting CNS antigens. It often causes inflammatory limbic encephalitis, for which immunotherapy is effective. Objective: The main objective of the study is to determine the clinical and paraclinical characteristics of encephalitides associated with NMDAr, CASPR2 and LGI1 antibodies. Materials and methods: It are a descriptive, prospective and retrospective study, which started from January 2016 to December 2018. Results: Our cohort included 30 patients with a mean age of 44±18.05 years. The limbic encephalitis was acute in 73.3%. The patients presented mainly psychiatric and vigilance disorders, epileptic seizures, dysautonomia, and memory disorders. A temporal hyper signal (± extra limbic) was often found on MRI, with non-specific abnormalities in the EEG and an inflammatory CSF profile. FBDS, dyskinesias, and neuro myotonia were the discriminating signs. Neoplasia was found in 16.7% of the cases. Immunotherapy led to good results. Conclusion: This study aimed to know how to identify these entities in our country and establish an early and effective treatment for better outcomes. A study with large samples would be more beneficial.

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Section: Discussionmentioning

confidence: 99%