Undifferentiated pleomorphic sarcomas of the proximal femur, A case study

Abstract

Pleomorphic sarcomas are a subtype of soft tissue sarcomas occurring most commonly in the proximal thigh, with a male preponderance, common in 7th and 8th decades of life. It is a locally invasive tumour with a wide clinical presentation.

Incidental finding of an undifferentiated sarcoma during lower limb Doppler ultrasound: A case report

“…3 Recurrence rate of undifferentiated sarcoma has been reported to be approximately 50%, hence periodic follow-up is recommended after treatment. 9,18 On reflection, this case report is important to the body of knowledge because it further provides evidence of the existence of an undifferentiated sarcoma presenting as the cause of patient's symptoms during lower limb Doppler ultrasound. This further strengthens the need to carefully assess surrounding soft tissue structures along the course of the lower limb vasculature during DVT scans.…”

“…3 Recurrence rate of undifferentiated sarcoma has been reported to be approximately 50%, hence periodic follow-up is recommended after treatment. 9,18…”

“…1 The treatment of undifferentiated sarcoma involves complete surgical excision involving a wide margin, chemotherapy and radiotherapy where applicable (these depend on the grading), metastasis and the extent of the surrounding structure invasion. 9,18 Surgical resection of undifferentiated sarcoma is decided upon following a consideration of many factors such as the size, location, depth of invasion, extent of invasion of the surrounding structures, patient's performance, the need for skin grafting/ reconstruction and possible quality of patient's life after surgery. 3 Recurrence rate of undifferentiated sarcoma has been reported to be approximately 50%, hence periodic follow-up is recommended after treatment.…”

Undifferentiated Pleomorphic Sarcoma of the Distal Thigh: A Case Report

“…As in our case, the tumor originated in the thigh, which is a common site of UPS (the most common sites for UPS are the proximal femur, proximal humerus, and retroperitoneum). It is more likely for this tumor to appear later in life, especially in the seventh decade [ 6 ]. One of the aspects that sets our situation apart from others is that the patient was relatively young when compared to the typical age range.…”

“…The involvement of the lymph nodes must be thoroughly evaluated, not just for dissection but also to ensure that no spread has occurred [ 6 ]. Soft tissue sarcomas of the extremities must be entirely eradicated from the body in order to be cured [ 6 , 10 ]. Thankfully, there was no metastasis in our situation.…”