“…Rare disease is a health condition that affects a small number of people compared with other prevalent diseases in the general population (Baldovino, Moliner, Taruscio, Daina, & Roccatello, ). To date, between 5,000 and 8,000 distinct rare diseases have been documented with new ones reported regularly in the medical literature (Taruscio, Floridia, Salvatore, Groft, & Gahl, ). Although they are characterized by their rarity, the total number of patients affected is large [e.g., 25–50 millions in the United States (Fernandez‐Marmiesse, Gouveia, & Couce, ), 27–36 millions in the EU (Moliner & Waligora, ), and 16.8 millions in China (Yang, Su, Lee, & Bai, )].…”