Abstract:Model organisms such as the Gram-positive bacterium Bacillus
subtilis have been studied intensively for decades. However, even for
such model organisms no function has been identified for about one
fourth of all proteins. It has recently been realized that such
understudied proteins as well as poorly studied functions set a
limitation to our understanding of the requirements for cellular life,
and the Understudied Proteins Initiative has been launched. Obviously,
poorly studied proteins that are strongly expre… Show more
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