“…As the liver is one of the target organs for Cd and disturbances in the proper functioning of this organ have serious consequences for health (Brea et al, ; Chang et al, ; Targher et al, ), in the present review our attention has been focused on polyphenol‐rich food products as a possible effective strategy in the protection from Cd hepatotoxicity and treatment of this heavy metal‐induced liver damage. Owing to the ability of polyphenols to bind ions of divalent metals, including toxic metals (Borowska, Brzóska, & Tomczyk, ; Brzóska, Gałażyn‐Sidorczuk, et al, ; Dai, Dong, & Ma, ; Horniblow, Henesy, Iqbal, & Tselepis, ; Jayanta & Shukla, ; Primikyri et al, ; Ravichandran, Rajendran, & Devapiriam, ), and strong antioxidative potential of these compounds (Brzóska, Borowska, & Tomczyk, , Brzóska, Rogalska, et al, ), as well as their abundance in dietary products (Brzóska, Borowska, & Tomczyk, ; Brzóska, Rogalska, et al, ; Quideau, Deffieux, Douat‐Casassus, & Pouységu, ), it seems to be of high importance to consider the possibility of using polyphenols as potential preventive and therapeutic agents against Cd hepatotoxicity. As the knowledge on the mechanisms of this xenobiotic‐induced liver damage is imperative when looking for possible factors effective in the protection from Cd hepatotoxicity, the pathways of this organ injury by Cd are also presented in the current paper.…”