“…Many patients described having feelings of anxiety, uncertainty or significant concern about their health problem [ 22 , 45 , 65 , 70 , 88 , 92 – 95 ]. Often patients had experienced pain or other discomforts which impacted their function and they desired immediate relief [ 22 , 42 , 45 , 70 – 73 , 88 , 93 , 94 , 96 , 97 ]. In some cases, they had attempted self-treatment at home, without good effect [ 73 , 86 , 96 , 98 ], or had sought out primary care without resolve [ 21 , 42 , 53 , 66 , 74 , 75 , 88 , 92 ].…”