Understanding the structure–property relationship in cortical bone to design a biomimetic composite

Libonati, Flavia; Vergani, L.

doi:10.1016/j.compstruct.2015.12.003

Cited by 57 publications

(25 citation statements)

References 60 publications

(108 reference statements)

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“…Having tested the crack propagation in homogeneous specimens, we now consider the fracture of heterogeneous materials composed of two constituent materials with very high mismatch in the elastic moduli, such as those occurring in biomaterials or engineering composites reinforced with high strength and high modulus fibers. We first consider a specimen designed to mimic the microstructure of cortical bone, following previous studies [27,28]. It is known that a high modulus mismatch in cortical bone structure causes crack deflection [27,28], which increases the toughness modulus of the material.…”

Section: Tensile Test Of a Bone-inspired Compositementioning

confidence: 99%

“…We first consider a specimen designed to mimic the microstructure of cortical bone, following previous studies [27,28]. It is known that a high modulus mismatch in cortical bone structure causes crack deflection [27,28], which increases the toughness modulus of the material. For the design of composites inspired by such structures and for the optimization of their toughness, it is crucial to predict the entire force-displacement curve accurately.…”

Section: Tensile Test Of a Bone-inspired Compositementioning

confidence: 99%

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Phase field modeling of crack propagation under combined shear and tensile loading with hybrid formulation

Jeong

Signetti

Han

et al. 2018

Computational Materials Science

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The crack phase field model has been well established and validated for a variety of complex crack propagation patterns within a homogeneous medium under either tensile or shear loading.However, relatively less attention has been paid to crack propagation under combined tensile and shear loading or crack propagation within composite materials made of two constituents with very different elastic moduli. In this work, we compare crack propagation under such circumstances modelled by two representative formulations, anisotropic and hybrid formulations, which have distinct stiffness degradation schemes upon crack propagation. We demonstrate that the hybrid formulation is more adequate for modeling crack propagation problems under combined loading because the residual stiffness of the damaged zone in the anisotropic formulation may lead to spurious crack growth and altered load-displacement response.

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Section: Tensile Test Of a Bone-inspired Compositementioning

confidence: 99%

Section: Tensile Test Of a Bone-inspired Compositementioning

confidence: 99%

Phase field modeling of crack propagation under combined shear and tensile loading with hybrid formulation

Jeong

Signetti

Han

et al. 2018

Computational Materials Science

View full text Add to dashboard Cite

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“…Cortical bone, which bears the major weight of the body, is considered the highest load-bearing tissue in the lower limb [44]. Despite the high strength, light weight, and extreme toughness of the cortical bone, it has the highest fracture risk [45]. In most cases, aging, accident, or diseases are the main causes of the bone failure.…”

Section: Natural Bones: Structure and Propertiesmentioning

confidence: 99%

“…In most cases, aging, accident, or diseases are the main causes of the bone failure. Although there are several attempts to study the mechanical behaviors as well as the macro-, micro-, and nanobone structures [44][45][46], reports revealed that the rate of bone fracture is rising every year. Thus, there is still need for thorough investigation on the biomaterials, implants design, and manufacturing.…”

Section: Natural Bones: Structure and Propertiesmentioning

confidence: 99%

A Review of Additive Mixed-Electric Discharge Machining: Current Status and Future Perspectives for Surface Modification of Biomedical Implants

Aliyu

Rani

Ginta

et al. 2017

Advances in Materials Science and Engineering

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Surface treatment remained a key solution to numerous problems of synthetic hard tissues. The basic methods of implant surface modification include various physical and chemical deposition techniques. However, most of these techniques have several drawbacks such as excessive cost and surface cracks and require very high sintering temperature. Additive mixed-electric discharge machining (AM-EDM) is an emerging technology which simultaneously acts as a machining and surface modification technique. Aside from the mere molds, dies, and tool fabrication, AM-EDM is materializing to finishing of automobiles and aerospace, nuclear, and biomedical components, through the concept of material migrations. The mechanism of material transfer by AM-EDM resembles electrophoretic deposition, whereby the additives in the AM-EDM dielectric fluids are melted and migrate to the machined surface, forming a mirror-like finishing characterized by extremely hard, nanostructured, and nanoporous layers. These layers promote the bone in-growth and strengthen the cell adhesion. Implant shaping and surface treatment through AM-EDM are becoming a key research focus in recent years. This paper reports and summarizes the current advancement of AM-EDM as a potential tool for orthopedic and dental implant fabrication. Towards the end of this paper, the current challenges and future research trends are highlighted.

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“…[40] Indeed, animals subjected to stresses that come from gravity force, such as human, bovine, and equine species show a characteristic osteonal structure, whereas fish species are characterized by a more lamellar one. [41] It has been shown that energy dissipation arising from the bone heterogeneity lead to markedly different biomechanical properties compared with a uniform material.…”

Section: Inspiration and Designmentioning

confidence: 99%

Bone‐Inspired Materials by Design: Toughness Amplification Observed Using 3D Printing and Testing

et al. 2016

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Inspired by the fact that nature provides multifunctional composites by using universal building blocks, the authors design and test synthetic composites with a pattern inspired by the microstructure of cortical bone. Using a high-resolution multimaterial 3D printer, the authors are able to manufacture samples and investigate their fracture behavior in mechanical tests. The authors' results demonstrate that the bone-inspired design is critical for toughness amplification and balance with material strength. The failure modes of the authors' synthetic composites show similarities with the cortical bone, like crack deflection and branching, constrained microcracking, and fibril bridging. The authors' results confirm that our design is eligible to reproduce the fracture and toughening mechanism of bone.

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Understanding the structure–property relationship in cortical bone to design a biomimetic composite

Cited by 57 publications

References 60 publications

Phase field modeling of crack propagation under combined shear and tensile loading with hybrid formulation

Phase field modeling of crack propagation under combined shear and tensile loading with hybrid formulation

A Review of Additive Mixed-Electric Discharge Machining: Current Status and Future Perspectives for Surface Modification of Biomedical Implants

Bone‐Inspired Materials by Design: Toughness Amplification Observed Using 3D Printing and Testing

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