Understanding the mechanical behavior of the material–tissue and material–material interface in dental reconstructions

Ferracane, Jack L.; Lohbauer, Ulrich; Palin, William M.

doi:10.1016/b978-0-08-100330-5.00005-4

Cited by 2 publications

(2 citation statements)

References 165 publications

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“…Since there is a variety of options for cementation, we rst determined the most biocompatible to HGF in a scratching assay. For this assay, we compared ZP, a gold standard 40 for implant prosthesis retention, and BC, which has been shown good cytocompatibility in our previous work 3 . As BC con rmed higher compatibility than ZP, it was utilized for all the following in vivo studies.…”

Section: Discussionmentioning

confidence: 99%

Dental cements as a late-stage peri-implant complication: A microtomographic and histopathological study in a rat model

Chandrashekar,

Biguetti,

Arteaga

et al. 2024

Preprint

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Cement mediated peri-implantitis accounts for 1.9–75% of dental implant failures associated with peri-implant diseases. This study evaluated the biological impact of dental cements on osseointegrated implants using Lewis rats. Twenty-two rats were distributed into 6 groups: negative control (NC), soft diet (SD), and hard diet (HD); positive control SD and HD (n = 3); Implant + bio-ceramic Cement (BC) SD and HD which included contralateral Sham sites (n = 5). Titanium implants were placed on either side of the maxillae and allowed to heal for 14 days. Later, both sides of experimental groups underwent a re-entry surgery to simulate clinical cementation. The right side received 0.60mg of BC. At 14 days post cement application, maxillae were harvested for clinical, microtomographic, and histological evaluations. Clinical and microtomographic evaluations indicated evidence of extensive inflammation and circumferential bone resorption around BC implants in comparison to NC. Histology revealed cement particles surrounded by inflammatory infiltrate in the implant area accompanied by biofilm for SD groups. Both sides of BC indicated intensive bone resorption accompanied by signs of osteolysis when compared to NC. Cemented groups depicted significantly lower bone to implant contact when compared to NC. In conclusion, residual cement extravasation negatively impacts osseointegrated implants after re-entry surgeries.

show abstract

Section: Discussionmentioning

confidence: 99%

Dental cements as a late-stage peri-implant complication: A microtomographic and histopathological study in a rat model

Chandrashekar,

Biguetti,

Arteaga

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Since there is a variety of options for cementation, we first determined the most biocompatible to HGF in a scratching assay. For this assay, we compared ZP, a gold standard 34 for implant prosthesis retention, and BC, which has been shown good cytocompatibility in our previous work 3 . As BC confirmed higher compatibility than ZP, it was utilized for all the following in vivo studies.…”

Section: Discussionmentioning

confidence: 99%

A microtomographic and histopathological evaluation of dental cements as late-stage peri-implant complication in a rat model

Lakkasetter Chandrashekar,

Biguetti,

Arteaga

et al. 2024

Sci Rep

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Cement mediated peri-implantitis accounts for 1.9–75% of dental implant failures associated with peri-implant diseases. This study evaluated the biological impact of dental cements on osseointegrated implants using Lewis rats. Twenty-two rats were distributed into 6 groups: negative control (NC) soft diet (SD), and hard diet (HD); positive control SD and HD (n = 3); Implant + bio-ceramic Cement (BC) SD and HD which included contralateral Sham sites (n = 5). Titanium implants were placed on either side of the maxillae and allowed to heal for 14 days. Later, both sides of experimental groups underwent a re-entry surgery to simulate clinical cementation. The right side received 0.60 mg of BC. At 14 days post cement application, maxillae were harvested for clinical, microtomographic, and histological evaluations. Clinical and microtomographic evaluations indicated evidence of extensive inflammation and circumferential bone resorption around BC implants in comparison to NC. Histology revealed cement particles surrounded by inflammatory infiltrate in the implant area accompanied by biofilm for SD groups. Both sides of BC indicated intensive bone resorption accompanied by signs of osteolysis when compared to NC. Cemented groups depicted significantly lower bone to implant contact when compared to NC. In conclusion, residual cement extravasation negatively impacted osseointegrated implants after re-entry surgeries.

show abstract

Understanding the mechanical behavior of the material–tissue and material–material interface in dental reconstructions

Cited by 2 publications

References 165 publications

Dental cements as a late-stage peri-implant complication: A microtomographic and histopathological study in a rat model

Dental cements as a late-stage peri-implant complication: A microtomographic and histopathological study in a rat model

A microtomographic and histopathological evaluation of dental cements as late-stage peri-implant complication in a rat model

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