Understanding Stimulation of Conjugal Gene Transfer by Nonantibiotic Compounds: How Far Are We?
Zhiming He,
Arnaud Dechesne,
Frank Schreiber
et al.
Abstract:A myriad of nonantibiotic compounds is released into the environment, some of which may contribute to the dissemination of antimicrobial resistance by stimulating conjugation. Here, we analyzed a collection of studies to (i) identify patterns of transfer stimulation across groups and concentrations of chemicals, (ii) evaluate the strength of evidence for the proposed mechanisms behind conjugal stimulation, and (iii) examine the plausibility of alternative mechanisms. We show that stimulatory nonantibiotic comp… Show more
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