Understanding Public Perspectives on Opt-Out Deceased Donor Transplant Policy

Butler, Catherine R.

doi:10.2215/cjn.11230922

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…Revision of the law in 2010 facilitated transplantation by family consent; however, the situation has not improved since this period. Substantial increases in donations cannot be expected unless an opt-out system, similar to those in other countries, is adopted [19]. A public opinion poll conducted in 2021 showed that only 5% of individuals who participated in the poll expressed their intention to donate organs, whereas over 60% of respondents expressed interest in transplantation and knew how to express their intention to donate organs [20].…”

Section: Starzl Et Al Performed the World's Rst Liver Transplant In 1...mentioning

confidence: 99%

Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan

Kawaguchi,

Terui,

Takenouchi

et al. 2023

Pediatr Surg Int

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Purpose: This study aimed to elucidate the di culties faced by adult native liver survivors with biliary atresia (BA) in Japan.Methods: A single-center, retrospective, observational study of 57 adult patients with BA was conducted.The clinical course of BA was compared between native liver survivors and non-survivors who reached adulthood. Indications and outcomes of liver transplantation (LT) among non-survivors were assessed.Results: A signi cantly larger portion of non-survivors (n=10) met the criteria for LT (p <0.001) and received treatment for portal hypertension after reaching 20 years of age (p <0.01) compared with the survivors. Causes of death included liver cirrhosis (n=8), graft failure of living donor liver transplantation (LDLT) (n=1), and hepatocarcinoma (n=1). Two of the non-survivors who died of liver cirrhosis had no indication for LT because of alcohol dependence and uncontrolled infection. An appropriate donor candidate could not be found for the ve patients who opted for LDLT. All six patients waitlisted for deceased donor liver transplantation (DDLT) died after a median waiting period of 17 months.Conclusion: Adult BA patients in Japan have limited options for LT, mainly owing to low donor candidate availability for LDLT and a low prevalence of DDLT.

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Section: Starzl Et Al Performed the World's Rst Liver Transplant In 1...mentioning

confidence: 99%

Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan

Kawaguchi,

Terui,

Takenouchi

et al. 2023

Pediatr Surg Int

View full text Add to dashboard Cite

show abstract

Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan

Kawaguchi,

Terui,

Takenouchi

et al. 2023

Preprint

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Purpose: This study aimed to elucidate the difficulties faced by adult native liver survivors with biliary atresia (BA) in Japan. Methods: A single-center, retrospective, observational study of 57 adult patients with BA was conducted. The clinical course of BA was compared between native liver survivors and non-survivors who reached adulthood. Indications and outcomes of liver transplantation (LT) among non-survivors were assessed. Results: A significantly larger portion of non-survivors (n=10) met the criteria for LT (p <0.001) and received treatment for portal hypertension after reaching 20 years of age (p <0.01) compared with the survivors. Causes of death included liver cirrhosis (n=8), graft failure of living donor liver transplantation (LDLT) (n=1), and hepatocarcinoma (n=1). Two of the non-survivors who died of liver cirrhosis had no indication for LT because of alcohol dependence and uncontrolled infection. An appropriate donor candidate could not be found for the five patients who opted for LDLT. All six patients waitlisted for deceased donor liver transplantation (DDLT) died after a median waiting period of 17 months. Conclusion: Adult BA patients in Japan have limited options for LT, mainly owing to low donor candidate availability for LDLT and a low prevalence of DDLT.

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Understanding Public Perspectives on Opt-Out Deceased Donor Transplant Policy

Cited by 2 publications

References 7 publications

Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan

Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan

Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan

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