Understanding local plant extinctions before it’s too late: bridging evolutionary genomics with global ecology.

Expósito-Alonso, Moisés

doi:10.32942/x2v885

Cited by 3 publications

(2 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ability of a species to withstand the challenges of climate change hinges on its genetic diversity 46 . The adaptation to shifting environments typically involves the gradual finetuning of molecular mechanisms, which occurs over evolutionary timescales.…”

Section: Discussionmentioning

confidence: 99%

Genotype-environment association across precipitation regimens reveals the mechanism of plant adaptation to rainy environments

Castellana,

Triozzi,

Dell’Acqua

et al. 2024

Preprint

View full text Add to dashboard Cite

In an era characterized by rapidly changing and less-predictable weather conditions fueled by the climate crisis, understanding the mechanisms underlying local adaptation in plants is of paramount importance for the conservation of species. As the frequency and intensity of extreme precipitation events increase, so are the flooding events resulting from soil water saturation. The deriving onset of hypoxic stress is one of the leading causes of crop damage and yield loss. By combining genomics and remote sensing data, today it is possible to probe natural plant populations that have evolved in different rainfall regimes and look for molecular adaptation to hypoxia. Here, using an environmental genome-wide association study (eGWAS) on 934 non-redundant georeferenced Arabidopsis ecotypes, we have identified functional variants for the geneMED25 BINDING RING-H2 PROTEIN 1(MBR1). This is a ubiquitin-protein ligase that regulates MEDIATOR25 (MED25), part of a multiprotein complex that interacts with transcription factors which act as key drivers of the hypoxic response in Arabidopsis, namely the RELATED TO AP2 proteins, RAP2.2 and RAP2.12. Through experimental validation, we show that natural variants ofMBR1have a differential impact on the stability of MED25 and, in turn, on hypoxic tolerance. Our study also highlights the pivotal role of the MBR1/MED25 module in establishing a comprehensive hypoxic response. Our findings show that molecular candidates for plant environmental adaptation can be effectively mined from large datasets. This thus supports the need for the integration of forward and reverse genetics with robust molecular physiology validation of the outcomes.

show abstract

Section: Discussionmentioning

confidence: 99%

Genotype-environment association across precipitation regimens reveals the mechanism of plant adaptation to rainy environments

Castellana,

Triozzi,

Dell’Acqua

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Moi's expertise in plant evolutionary ecology, biology and genetics, combined with computational approaches, informs his research programme, which aims to forecast the evolutionary outcomes of populations under climate change, and to ultimately anticipate potential future biodiversity losses. These themes are explored in Moi's Tansley insight ‘Understanding local plant extinctions before it's too late: bridging evolutionary genomics with global ecology’ (Exposito‐Alonso, 2023b, in this issue pp. 2005–2011).…”

mentioning

confidence: 99%

The New Phytologist Tansley Medal 2022 – Leander D. L. Anderegg and Moi Exposito‐Alonso

Slater¹,

Dolan²

2023

New Phytologist

View full text Add to dashboard Cite

Genomic variation of a keystone forest tree species reveals signals of local adaptation despite high levels of phenotypic plasticity

Mueller¹,

Geßner²,

Mäder³

et al. 2023

Preprint

View full text Add to dashboard Cite

Local adaptation is key for ecotypic differentiation and species evolution. Understanding the underlying genomic patterns allows the prediction of future maladaptation and ecosystem stability. Here we report the whole-genome resequencing of 865 individuals from 100 range-wide populations of European beech (Fagus sylvatica), which is one of the most important forest tree species in Europe. We show that genetic variation closely mirrors geography. Adaptive variation identified by genotype-environment associations exhibits highly polygenic architectures, involving thousands of associated sequence variants across the genome. By modelling the genomic offset of these sequence variants under projected future climate conditions, we identify broad- and fine-scale variation highlighting geographic regions as well as populations at potential elevated risk of mortality or local extinction. Our results emphasize the importance of considering natural genetic variation for forest conservation under climate change conditions.

show abstract

Understanding local plant extinctions before it’s too late: bridging evolutionary genomics with global ecology.

Cited by 3 publications

References 39 publications

Genotype-environment association across precipitation regimens reveals the mechanism of plant adaptation to rainy environments

Genotype-environment association across precipitation regimens reveals the mechanism of plant adaptation to rainy environments

The New Phytologist Tansley Medal 2022 – Leander D. L. Anderegg and Moi Exposito‐Alonso

Genomic variation of a keystone forest tree species reveals signals of local adaptation despite high levels of phenotypic plasticity

Contact Info

Product

Resources

About