Understanding hypergammaglobulinemia in experimental or natural visceral leishmaniasis
Camila Aparecida de Carvalho,
Roberto Mitsuyoshi Hiramoto,
Luciana Regina Meireles
et al.
Abstract:Nonspecific hypergammaglobulinemia (HGG) occurs in symptomatic human visceral leishmaniasis (VL) caused by L. L. infantum. This study assessed this finding in experimental infection in hamsters and natural infection in dogs. The serum concentration of proteins, albumin and globulins was determined through the biuret and bromocresol green reaction, where the HGG was better expressed through the albumin/globulin (A/G) ratio. HGG was associated with a higher concentration of specific anti‐glycan antibodies (BSA‐G… Show more
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