Understanding anthelmintic resistance in livestock using “omics” approaches

Mukherjee, Ayan; Kar, Indrajit; Patra, Amlan Kumar

doi:10.1007/s11356-023-31045-y

Cited by 1 publication

(1 citation statement)

References 236 publications

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“…In veterinary medicine, metabolomic research is still limited, although its potential, as previously stated, is widely recognized [18,19].…”

Section: Methodsmentioning

confidence: 99%

Nuclear Magnetic Resonance (NMR) Metabolomics: Current Applications in Equine Health Assessment

Laus,

Bazzano,

Spaterna

et al. 2024

Metabolites

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Metabolomics can allow for the comprehensive identification of metabolites within biological systems, at given time points, in physiological and pathological conditions. In the last few years, metabolomic analysis has gained popularity both in human and in veterinary medicine, showing great potential for novel applications in clinical activity. The aim of applying metabolomics in clinical practice is understanding the mechanisms underlying pathological conditions and the influence of certain stimuli (i.e., drugs, nutrition, exercise) on body systems, in the attempt of identifying biomarkers that can help in the diagnosis of diseases. Proton Nuclear Magnetic Resonance spectroscopy (1H-NMR) is well tailored to be used as an analytical platform for metabolites’ detection at the base of metabolomics studies, due to minimal sample preparation and high reproducibility. In this mini-review article, the scientific production of NMR metabolomic applications to equine medicine is examined. The research works are very different in methodology and difficult to compare. Studies are mainly focused on exercise, reproduction, and nutrition, other than respiratory and musculoskeletal diseases. The available information on this topic is still scant, but a greater collection of data could allow researchers to define new reliable markers to be used in clinical practice for diagnostic and therapeutical purposes.

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“…In veterinary medicine, metabolomic research is still limited, although its potential, as previously stated, is widely recognized [18,19].…”

Section: Methodsmentioning

confidence: 99%