The unprecedented challenges posed by climate change necessitate agricultural adaptation by farmers, especially in the regions of Asia, where rain-fed agriculture is the principal source of food production. Studying adaptation not only assists in knowing how farmers are dealing with the repercussions of climate change, but also provides the baseline for the planned interventions which are essential in this era of human-instigated climate change. We used case study data to examine whether and how subsistence-oriented smallholder farmers in three agro-ecological zones of Nepal (Terai, Hill, and Mountain) are developing and implementing adaptation strategies. The findings from small farm household interviews (n = 384), key informant interviews (n = 33), and focus group discussions (n = 3) suggest that farmers are dealing with the challenges facing their traditional agricultural practices. The main adaptation strategies include changing crop types and varieties, adding fertilizers, the use of new technologies, soil and water management, diversification of income sources, and migration. Both climatic and nonclimatic factors were found to influence these subsistence smallholder farmers' adaptation practices. However, climatic factors that are beyond individual control threatened the livelihood of rural farmers who predominantly rely on natural resources for their livelihood and income. The findings highlight the interplay of multiple agents: local farmers, community-based organizations, and the local and ABOUT THE AUTHORS Sikha Karki holds a master's degree in Biodiversity and Environment Management from the University of Bergen, Norway and Tribhuvan University, Nepal. Currently, she is doing her PhD at Griffith University, Australia. Her research focuses on the impacts of climate change and food security on farm households in Nepal.