Underpinning the Food Matrix Regulation of Postexercise Myofibrillar Protein Synthesis by Comparing Salmon Ingestion With the Sum of Its Isolated Nutrients in Healthy Young Adults

Plant Protein Blend Ingestion Stimulates Postexercise Myofibrillar Protein Synthesis Rates Equivalently to Whey in Resistance-Trained Adults

“…The present data join a growing body of work which fail to confirm the directional (or at least quantitative) association between the speed, magnitude, and/or overall postprandial leucine response and the stimulation of (postexercise) MPS (22). Interestingly, the lack of support for the "leucine trigger hypothesis" has, to date, mainly come via studies that have used protein-rich whole foods (29,46,48,49,(66)(67)(68), in contrast to the present study which provided isolated protein sources. We are not the first, however, to show lesser systemic leucine (and other EAAs) responses in tandem with comparable postprandial (and postexercise) stimulations of MPS after concentrated/isolated plant vs animal protein ingestion, with >25 g of potato (69), pea (29), and soy (14) protein as examples.…”

Ingestion of a variety of non-animal-derived dietary protein sources results in diverse postprandial plasma amino acid responses which differ between young and older adults

“…However, contrary to our hypothesis, and not in line with our previous work ( 29 , 30 ) , milk ingestion resulted in a ∼19 % lower postprandial total amino acid availability than mycoprotein, likely attributed to the manner in which the milk protein was provided. Given milk is typically consumed as a nutrient-dense food and recent work demonstrating a robust MPS response following whole-food ingestion ( 14 , 30 , 32 , 40 , 53 , 54 ) , we provided a whole food as opposed to an isolated milk protein beverage (as we had in previous work). However, this resulted in higher carbohydrate and fat contents in the milk drink ( Table 3 ), which likely dampened the plasma aminoacidaemic response, as these macronutrients have been demonstrated to delay gastric emptying and/or protein digestion and amino acid absorption ( 43 , 55 , 56 ) .…”

High-Moisture Extrusion of a Dietary Protein Blend Impairs In Vitro Digestion and Delays In Vivo Postprandial Plasma Amino Acid Availability in Humans

“…These structural changes can influence the postprandial amino acid availability and, likely, the consequent metabolic fate of the ingested amino acids. For example, faster and greater rises in postprandial plasma amino acid concentrations have been demonstrated to result in a greater increase in amino acid oxidation [ 49 ] and are often suggested to produce a greater anabolic response [ 5 ]. Furthermore, the majority of dietary protein we ingest is contained within nutrient-dense, structurally complex food/protein matrices that have undergone (multiple) processing methods.…”