Underestimation of Schistosoma mansoni prevalences

Vlas, Sake J. de; Gryseels, B.

doi:10.1016/0169-4758(92)90144-q

Cited by 248 publications

(182 citation statements)

References 24 publications

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“…Due to time and financial constraints, only one stool sample per person could be examined. Repeated stool analysis with the Kato-Katz technique has shown to substantially increase sensitivity (de Vlas and Gryseels, 1992;Marti and Koella, 1993); hence we can assume that the 'true' prevalence may be higher than assessed in the present study.…”

Section: Prevalence and Impact Of Opisthorchis Viverrinimentioning

confidence: 73%

Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR

Sayasone

Odermatt

Phoumindr

et al. 2007

Transactions of the Royal Society of Tropical Medicine and Hygi

131

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a v a i l a b l e a t w w w . s c i e n c e d i r e c t . c o m j o u r n a l h o m e p a g e : w w w . e l s e v i e r h e a l t h . c o m / j o u r n a l s / t r s t Summary In Lao PDR, detailed investigations on Opisthorchis viverrini are scarce. The objective was to document epidemiological features of O. viverrini infections in a highly endemic district. A random sample was selected (13 villages, 15 households/village, all household members aged >6 months). Clinical examinations, short interviews and stool examinations (Kato-Katz technique) were performed. Fish samples were dissected for the presence of metacercaria. In total, 814 persons were enrolled (median age 16 years, 51.5% women). The prevalence was 58.5%. Infection rates increased with age (from 20.0 to 85.5%; P < 0.001). Intensity of infection and the habit of consuming insufficiently cooked fish also increased with age. Of the study participants, 75.2% reported cooking fish insufficiently. Of the 23 different species of cyprinoid fish consumed in the study villages, 20 species were infected. At the village level, the prevalence of raw fish consumption was strongly associated with the infection status of O. viverrini (r = 0.76, P = 0.003). At individual level, age, the consumption of insufficiently cooked fish, and the absence of sanitation were strongly associated. The disease associated with O. viverrini infection needs to be assessed in order to develop and conduct adequate interventions. Epidemiology of

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Section: Prevalence and Impact Of Opisthorchis Viverrinimentioning

confidence: 73%

Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR

Sayasone

Odermatt

Phoumindr

et al. 2007

Transactions of the Royal Society of Tropical Medicine and Hygi

131

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“…Assessment of S. mansoni infection using a single KatoKatz slide per individual collected on a single day could be a limitation of this study as some light infections could have been missed [35,42] .…”

Section: Discussionmentioning

confidence: 99%

Efficacy and side effects of praziquantel in the treatment of Schistosomiasis mansoni in schoolchildren in Shesha Kekele Elementary School, Wondo Genet, Southern Ethiopia

Erko

Degarege

Tadesse

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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“…The observed prevalence of 42% could be an underestimation of the actual prevalence of the infection in this area, because we used the Kato-Katz method, which has shown low sensitivity when a single stool sample is obtained. 18,19 This study also showed that S. mansoni-related liver pathology was relatively high in this population compared with that observed elsewhere. 20,21 The prevalence of infection in our study population followed a convex distribution: peaking at ages 15-18 years and declining thereafter.…”

Section: Discussionmentioning

confidence: 48%

“…18,39 Studies have shown that this method is less sensitive and less accurate when one stool sample is used, resulting in an underestimation of the prevalence. 18 The low sensitivity using the Kato-Katz method is attributed to a number of reasons, such as daily variation in egg output and inability to detect light infections. 19,40 Sensitivity can be enhanced by examining multiple stool samples and smears.…”

Section: Discussionmentioning

confidence: 99%

High Schistosoma mansoni Disease Burden in a Rural District of Western Zambia

Mutengo¹,

Mwansa²,

Mduluza³

et al. 2014

The American Society of Tropical Medicine and Hygiene

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Abstract. Schistosoma mansoni disease is endemic in most parts of rural Zambia, and associated complications are common. We conducted a cross-sectional study among 754 people in rural communities of Kaoma District, western Zambia to determine the burden of S. mansoni infection and associated morbidity. Parasitology and ultrasonography assessments were conducted on consenting participants. The overall prevalence of S. mansoni infection and geometric mean egg count (GMEC) were 42.4% (304) and 86.6 eggs per gram (95% confidence interval = 75.6-99.6), respectively. Prevalence was highest in the age group of 15-19 years old (adjusted prevalence ratio = 1.70, P = 0.017). S. mansonirelated portal fibrosis was detected in 26% of the participants screened. Participants above 39 years old were 2.93 times more likely to have fibrosis than the 7-9 years old age group (P = 0.004). The study highlights the high burden of S. mansoni disease in this area and calls for immediate interventions to avert complications associated with the disease.

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Underestimation of Schistosoma mansoni prevalences

Cited by 248 publications

References 24 publications

Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR

Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR

Efficacy and side effects of praziquantel in the treatment of Schistosomiasis mansoni in schoolchildren in Shesha Kekele Elementary School, Wondo Genet, Southern Ethiopia

High Schistosoma mansoni Disease Burden in a Rural District of Western Zambia

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