Under-Diagnosis of Sleep Apnea in Patients After Acute Myocardial Infarction

Konečný, Tomáš; Kuniyoshi, Fatima H. Sert; Orban, Marek; Pressman, Gregg S.; Kára, Tomáš; Gami, Apoor S.; Caples, Sean M.; López-Jiménez, Francisco; Somers, Virend K.

doi:10.1016/j.jacc.2010.04.032

Cited by 103 publications

(73 citation statements)

References 5 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Sleep difficulties are a common feature of PTSD, 41 and are also a common complaint after ACS. 102,103 While sleep difficulties have been shown to be associated with CVD events, 44 no study has yet tested poor sleep as a mediator of the association of ACSinduced PTSD and adverse CVD outcomes.…”

Section: Behavioral Risk Factorsmentioning

confidence: 99%

Posttraumatic Stress Disorder and Cardiovascular Disease

Edmondson¹,

Hiti²,

Kronish³

2015

Prevention of Cardiovascular Diseases

View full text Add to dashboard Cite

Posttraumatic stress disorder (PTSD) is an anxiety disorder initiated by exposure to a traumatic event and characterized by intrusive thoughts about the event, attempts to avoid reminders of the event, and physiological hyperarousal. In a number of large prospective observational studies, PTSD has been associated with incident cardiovascular disease (CVD) and mortality. Also, in recent years, a number of studies have shown that cardiovascular events can themselves cause PTSD in more than 1 in 8 patients with acute coronary syndrome. Further, a few small studies suggest that PTSD secondary to an acute CVD event then places patients at increased risk for subsequent CVD events and mortality. In this article, we review the evidence for a link between PTSD and CVD, and discuss potential mechanisms for that association as well as future directions for research.Posttraumatic stress disorder is an anxiety disorder initiated by an exposure to a traumatic event, such as combat, natural disaster, or sexual assault, and is characterized by symptoms such as re-experiencing the traumatic event (e.g., intrusive thoughts, nightmares), cognitive or behavioral avoidance of reminders of the event, and physiological hyperarousal. It is associated with abnormal amygdala, prefrontal cortex, and hippocampal function 1 as well as abnormal neuroendocrinologic characteristics. 2 Increasingly, PTSD is also being recognized as an independent risk factor for cardiovascular disease (CVD). [3][4][5] This paper outlines our current understanding of the association of PTSD and CVD, and considers 2 propositions concerning the association: (1) PTSD due to traumatic life events increases risk for incident CVD, and (2) the experience of life-threatening CVD may cause PTSD, and increase recurrent CVD risk. PTSD and risk for incident CVD/mortalityIn recent years, evidence has accumulated that PTSD due to various types of traumatic experiences, including exposure to combat, the World Trade Center attacks, and other similar life-threatening events is associated with development of cardiovascular disease, acute coronary syndromes, and cardiac-specific mortality. To date, 5 prospective cohort

show abstract

Section: Behavioral Risk Factorsmentioning

confidence: 99%

Posttraumatic Stress Disorder and Cardiovascular Disease

Edmondson¹,

Hiti²,

Kronish³

2015

Prevention of Cardiovascular Diseases

View full text Add to dashboard Cite

show abstract

“…The identifi cation of OSA in these patients is important because risk may be mitigated by treatment with continuous positive airway pressure. 11 In a recent chart review study of patients admitted with acute myocardial infarction (MI), OSA was found to be signifi cantly underdiagnosed when prospectively evaluated by overnight polysomnography (PSG). 11 Similarly, patients admitted to the hospital with chronic obstructive pulmonary disease (COPD) exacerbations have been found to have increased prevalence of ; Mohammed Cheema, MD 1 ; Raymond Malloy, RRT 1 testing.…”

mentioning

confidence: 99%

Obstructive Sleep Apnea in Obese Hospitalized Patients: A Single Center Experience

Sharma

Mather

Efird

et al. 2015

Journal of Clinical Sleep Medicine

View full text Add to dashboard Cite

“…25 SDB is highly prevalent in patients with ischemic heart disease and oft en remains undiagnosed, even aft er admission for myocardial infarction. 26 …”

Section: Coronary Artery Diseasementioning

confidence: 99%

“…38 Indeed, patients after myocardial infarction, who in prospective studies also manifest a very high SDB prevalence, may often be significantly underdiagnosed in the real-world setting ( Fig 2 ). 26 Further studies are needed to define how many patients with HCM have undiagnosed SDB and to estimate which subgroup of patients with HCM could benefit from routine sleep apnea screening ( Fig 1 ).…”

Section: Prevalencementioning

confidence: 99%

Sleep-Disordered Breathing in Hypertrophic Cardiomyopathy

Konečný

Somers

2014

Chest

Self Cite

View full text Add to dashboard Cite

Sleep-disordered breathing (SDB) may be a treatable risk factor in patients with hypertrophic cardiomyopathy (HCM), the most common inherited cardiomyopathy. Evidence suggests a high prevalence of SDB in HCM. We summarize the pathophysiology of SDB as it relates to hypertension, coronary artery disease, atrial fi brillation, and sudden cardiac death in patients with HCM. The implications regarding the care of patients with HCM and SDB are discussed as well as the knowledge defi cits needing further exploration.CHEST 2014; 146 ( 1 )

show abstract

Under-Diagnosis of Sleep Apnea in Patients After Acute Myocardial Infarction

Cited by 103 publications

References 5 publications

Posttraumatic Stress Disorder and Cardiovascular Disease

Posttraumatic Stress Disorder and Cardiovascular Disease

Obstructive Sleep Apnea in Obese Hospitalized Patients: A Single Center Experience

Sleep-Disordered Breathing in Hypertrophic Cardiomyopathy

Contact Info

Product

Resources

About