Abstract:Serine proteases are the most predominant class performing a number of activities in organisms. Undergoing several mutations in their sequence over a span of a billion years yet S1 chymotrypsin/trypsin family has maintained a common fold. Granule Associated Serine Peptidases of Immune Defense (GASPIDS) belonging to the S1 class, found in the granules of immune cells are explicitly involved in the regulation of immune-related functions possessing a conserved catalytic triad Ser-Asp-His. The neutrophils along wi… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.