Uncovering immune characteristics of neurons in the context of multiple sclerosis and experimental autoimmune encephalomyelitis
Abdulshakour Mohammadnia,
Sienna Sage Drake,
Stephanie E.J. Zandee
et al.
Abstract:Multiple sclerosis (MS) is an immune-mediated disease characterized by chronic inflammation and damage to the central nervous system, and substantial characterization of molecular signatures of glial and immune cells in the disease has been conducted. However, comparatively less well characterized is the molecular signature of pathologically inflamed neurons. Here, we accessed multi-omic high-throughput transcriptomic and epigenomic data to investigate the molecular signature of neurons from progressive MS pat… Show more
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