“…Consequently, a deeper understanding of the lncRNA-associated gene-modulatory processes will support the development of viable prognostic biological markers and personalized therapies for patients with HCC. LINC00294, a newly described long intergenic non-protein coding RNA identified in recent years, has been reported to be related to atherosclerotic plaque and ischemic stroke and the activation of human retinal vascular endothelial cells [ 13 , 14 ]. Bakkenolide-IIIa-mediated upregulation of LINC00294 expression was shown to ameliorate LPS-induced inflammatory injury in human umbilical vein endothelial cells [ 15 ].…”