Uncovering burden disparity: A comparative analysis of the impact of moderate-to-severe psoriasis and hidradenitis suppurativa

Hamzavi, Iltefat; Sundaram, Murali; Nicholson, Cynthia L.; Zivkovic, Marko; Parks-Miller, Angela; Lee, Jianyi; Yi, Jingbo; Gu, Yihua; Okun, Martin; Ganguli, Arijit; Arikian, Steven R.

doi:10.1016/j.jaad.2017.07.027

Cited by 44 publications

(35 citation statements)

References 59 publications

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“…The QoL impact of HS was much greater than the impact of several other dermatologic conditions . Patients with HS have a higher HRQoL burden than patients with psoriasis . Compared with an age‐standardized general population, HS patients scored significantly worse on several dimensions of the generic 15D questionnaire.…”

Section: Resultsmentioning

confidence: 98%

“…62 Patients with HS have a higher HRQoL burden than patients with psoriasis. 63 Compared with an age-standardized general population, HS patients scored significantly worse on several dimensions of the generic 15D questionnaire. A significant difference compared to psoriasis patients was detected on the sexual activity dimension.…”

Section: Comparison Of Qol In Hs Other Diseases and Controlsmentioning

confidence: 91%

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Quality of life measurement in hidradenitis suppurativa: position statement of the European Academy of Dermatology and Venereology task forces on Quality of Life and Patient‐Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa

Chernyshov

Zouboulis

Tómas-Aragonés

et al. 2019

Acad Dermatol Venereol

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This paper is organized jointly by the European Academy of Dermatology and Venereology (EADV) Task Force (TF) on Quality of Life (QoL) and Patient‐Oriented Outcomes and the EADV TF on acne, rosacea and hidradenitis suppurativa (ARHS). The purpose of this paper was to present current knowledge about QoL assessment in HS, including data on HS‐specific health‐related (HR) QoL instruments and HRQoL changes in clinical trials, and to make practical recommendations concerning the assessment of QoL in people with HS. HS results in significant quimp that is higher than in most other chronic skin diseases. HS impact in published studies was assessed predominantly (84% of studies) by the Dermatology Life Quality Index (DLQI). There is a lack of high‐quality clinical trials in HS patients where HRQoL instruments have been used as outcome measures. One double‐blind randomized placebo‐controlled trial on infliximab with low number of participants reported significantly better HRQoL improvement in the treatment group than in the placebo group. Well‐designed clinical studies in HS patients to compare different treatment methods, including surgical methods and assessing long‐term effects, are needed. Because of lack of sufficient validation, the Task Forces are not at present able to recommend existing HS‐specific HRQoL instruments for use in clinical studies. The EADV TFs recommend the dermatology‐specific DLQI questionnaire for use in HS patients. The EADV TFs encourage the further development, validation and use of other HS‐specific, dermatology‐specific and generic instruments but such use should be based on the principles presented in the previous publications of the EADV TF on QoL and Patient‐Oriented Outcomes.

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Section: Resultsmentioning

confidence: 98%

Section: Comparison Of Qol In Hs Other Diseases and Controlsmentioning

confidence: 91%

Quality of life measurement in hidradenitis suppurativa: position statement of the European Academy of Dermatology and Venereology task forces on Quality of Life and Patient‐Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa

Chernyshov

Zouboulis

Tómas-Aragonés

et al. 2019

Acad Dermatol Venereol

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“…As no curative treatment has yet been developed, HS patients suffer from chronic and debilitating pain. HS significantly affects quality of life, promoting severe psychosocial impairment . Furthermore, associations have been described between HS and various autoimmune diseases and metabolic syndromes, including obesity, hyperlipidaemia, diabetes, hypertension, inflammatory bowel disease, arthritis and spondyloarthropathy …”

Section: Introductionmentioning

confidence: 99%

“…HS significantly affects quality of life, promoting severe psychosocial impairment. 5,6 Furthermore, associations have been described between HS and various autoimmune diseases and metabolic syndromes, including obesity, hyperlipidaemia, diabetes, hypertension, inflammatory bowel disease, arthritis and spondyloarthropathy. 1,[7][8][9][10][11][12][13] To date, few studies have explored the epidemiology of HS in Asian populations, although racial differences in HS rates have been reported in previous studies.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and comorbidities associated with hidradenitis suppurativa in Korea: a nationwide population‐based study

Lee

Kwon

Jung

et al. 2018

Acad Dermatol Venereol

107

173

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“…Even though that makes smoking seem much less worrisome than the statement about twofold increased risk, it still assumes that smoking causes hidradenitis, and while Garg et al . attempted to exclude those who were already diagnosed with hidradenitis, we cannot exclude the alternative that having hidradenitis, a truly horrible disease, makes people more likely to smoke.…”

mentioning

confidence: 99%

Hidradenitis and smoking

2018

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Uncovering burden disparity: A comparative analysis of the impact of moderate-to-severe psoriasis and hidradenitis suppurativa

Cited by 44 publications

References 59 publications

Quality of life measurement in hidradenitis suppurativa: position statement of the European Academy of Dermatology and Venereology task forces on Quality of Life and Patient‐Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa

Quality of life measurement in hidradenitis suppurativa: position statement of the European Academy of Dermatology and Venereology task forces on Quality of Life and Patient‐Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa

Prevalence and comorbidities associated with hidradenitis suppurativa in Korea: a nationwide population‐based study

Hidradenitis and smoking

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