Uncomplicated diverticular disease is not a common cause of colonic symptoms

Kang, Jin-Yong; Firwana, Belal; Green, A. E.; Matthews, H R; Poullis, A; Barnabas, Ashley; Tan, Lian Tat; Lim, Aaron

doi:10.1111/j.1365-2036.2010.04540.x

Cited by 15 publications

(11 citation statements)

References 13 publications

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“…conducted a population‐based study of 2267 questionnaire respondents, showing that both functional constipation and constipation‐predominant IBS were not associated with diverticulosis . Several prior studies and our own findings have suggested that constipation is not positively associated with diverticulosis …”

Section: Discussionmentioning

confidence: 68%

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Association between colonic diverticulosis and bowel symptoms: A case‐control study of 1629 Asian patients

Nagata

Niikura

Aoki

et al. 2015

J of Gastro and Hepatol

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This large, colonoscopy-based, case-control study demonstrated that neither constipation nor hard stools were associated with an increased risk of diverticulosis, regardless of diverticulum location. In females, but not males, diarrhea and loose stools were positively associated with diverticulosis. Long-term test-retest reliability suggested that these symptoms remain consistent over a given period.

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Section: Discussionmentioning

confidence: 68%

“…Another study from Kang et al . showed the frequency of constipation and constipation‐predominant IBS was similar in patients with and without diverticulosis . Jung et al .…”

Section: Discussionmentioning

confidence: 90%

Association between colonic diverticulosis and bowel symptoms: A case‐control study of 1629 Asian patients

Nagata

Niikura

Aoki

et al. 2015

J of Gastro and Hepatol

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“…An important subgroup amounting to around 20% of patients with diverticulosis suffer from recurrent short‐lived abdominal pain. Some authors have suggested that the occurrence of symptoms in patients without evidence of acute diverticulitis is incidental 35 . There is, however, a growing body of evidence which suggests that those patients with symptomatic disease have distinct abnormalities in motor function, inflammatory, neural, and psychologic changes that differ from asymptomatic patients.…”

Section: Discussionmentioning

confidence: 99%

“…Some authors have suggested that the occurrence of symptoms in patients without evidence of acute diverticulitis is incidental. 35 There is, however, a growing body of evidence which suggests that those patients with symptomatic disease have distinct abnormalities in motor function, inflammatory, neural, and psychologic changes that differ from asymptomatic patients. Previous theories of the etiol-ogy of symptoms in diverticular disease have focused on the role of structural and luminal changes in the condition, particularly, the role of high pressure colonic contractions.…”

Section: Previous Literaturementioning

confidence: 99%

Visceral hypersensitivity in symptomatic diverticular disease and the role of neuropeptides and low grade inflammation

Humes¹,

Simpson²,

Smith³

et al. 2012

Neurogastroenterology Motil

112

100

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“…42 The study used Rome criteria for IBS to classify patients and the response rates were high. Subjects completed questionnaires prior to structural exams.…”

Section: Chronic Symptomsmentioning

confidence: 99%

Diverticular Disease: Reconsidering Conventional Wisdom

Peery

Sandler

2013

Clinical Gastroenterology and Hepatology

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Colonic diverticula are common in developed countries and complications of colonic diverticulosis are responsible for a significant burden of disease. Several recent publications have called into question long held beliefs about diverticular disease. Contrary to conventional wisdom, studies have not shown that a high fiber diet protects against asymptomatic diverticulosis. The risk of developing diverticulitis among individuals with diverticulosis is lower than the 10–25% commonly quoted, and may be as low as 1% over 11 years. Nuts and seeds do not increase the risk of diverticulitis or diverticular bleeding. It is unclear whether diverticulosis, absent diverticulitis or overt colitis, is responsible for chronic gastrointestinal symptoms or worse quality of life. The role of antibiotics in acute diverticulitis has been challenged by a large randomized trial that showed no benefit in selected patients. The decision to perform elective surgery should be made on a case-by-case basis and not routinely after a second episode of diverticulitis, when there has been a complication, or in young people. A colonoscopy should be performed to exclude colon cancer after an attack of acute diverticulitis but may not alter outcomes among individuals who have had a colonoscopy prior to the attack. Given these surprising findings, it is time to reconsider conventional wisdom about diverticular disease.

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Uncomplicated diverticular disease is not a common cause of colonic symptoms

Abstract: SUMMARY BackgroundColonic diverticular disease is common among older individuals whereas colonic symptoms, such as those of irritable bowel syndrome, are frequent in the general population.

Cited by 15 publications

References 13 publications

Association between colonic diverticulosis and bowel symptoms: A case‐control study of 1629 Asian patients

Association between colonic diverticulosis and bowel symptoms: A case‐control study of 1629 Asian patients

Visceral hypersensitivity in symptomatic diverticular disease and the role of neuropeptides and low grade inflammation

Diverticular Disease: Reconsidering Conventional Wisdom

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