Uncommon Tumors

Identification of MGB1 as a Marker in the Differential Diagnosis of Lung Tumors in Patients with a History of Breast Cancer by Analysis of Publicly Available SAGE Data

“…Moreover, metastatic breast cancer can grow along with the alveolar septa, in a similar manner to bronchioloalveolar carcinomas. 6 Difficulty is also caused by the need to carry out a differential diagnosis on biopsy specimens. Often, lung biopsies produce small amounts of fragmented tissue, which contain only a few degenerated cancer cells.…”

Endobronchial chondromatous hamartoma in an infant

“…2,7 The term ''hamartoma'' was first used by Albrecht in 1904 to describe a malformation comprised of abnormal growth of tissues that are native to a given organ. 8 Benign mesenchymoma or ''adult'' hamartoma is considered the commonest benign tumor in the adult lung. 8,9 It usually occurs in the fifth or sixth decades of life.…”

“…8 Benign mesenchymoma or ''adult'' hamartoma is considered the commonest benign tumor in the adult lung. 8,9 It usually occurs in the fifth or sixth decades of life. 8,[10][11][12] These are mainly solitary in location and considered to be very slowgrowing lesions.…”

Giant lamellar bodies as a feature of pulmonary low‐grade MALT lymphomas

“…Histopathologically, GLBs are roughly spherical, eosinophilic whorled structures occurring singly or in clusters within alveolar ducts and spaces, which have been reported as staining strongly for surfactant apoprotein A and weakly for surfactant apoprotein B. 3,4,7 Ultrastructurally, they comprise concentric laminated layers of extracellular material. 1,6,7 Our ®ndings con®rm that the features of GLBs in MALT lymphomas are similar to those seen in other disorders, although we found no staining for surfactant apoprotein B, as opposed to that described by Guccion.…”

“…Giant lamellar bodies are pulmonary inclusion bodies that are occasionally identi®ed in association with certain forms of pulmonary disorders. They are most commonly seen in association with sclerosing haemangiomas with an incidence of 24%, 1,2 but have been identi®ed also in a few cases of plasma cell granuloma 3 and alveolar adenoma, 4 as well as in association with alveolar proteinosis. 5,6 Recently, GLBs were described in association with a pulmonary lymphoma of mucosaassociated lymphoid tissue (MALT) origin.…”