Unclassified pediatric renal stromal tumor overlapping with metanephric stromal tumor and solitary fibrous tumor with diffuse S-100 protein expression

Brancato, Franca; Gurrera, A; Bisceglia, Michele; Alaggio, Rita; Cataldo, Andrea Di; Benedetto, Vincenzo Di; Magro, Gaetano

doi:10.1016/j.prp.2011.07.008

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…1 In recent years, several cases of MST occurring in adults have been reported [2][3][4] as well as cases of MST-like lesions with atypical features. 5 We report a case of "metanephric stromal tumor, cellular type," a novel variant of MST, presenting in a postmenopausal woman.…”

Section: Introductionmentioning

confidence: 99%

Cellular Metanephric Stromal Tumor in a Postmenopausal Woman

2012

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Metanephric stromal tumor (MST) of the kidney is a rare pediatric neoplasm which has rarely been reported in adults. The authors present a case of MST, cellular type, an unreported variant, in a 56-year-old postmenopausal woman. The 9.0-cm tumor was solid, unencapsulated, and well circumscribed, with a firm homogeneous cut surface. The tumor was purely stromal with dense spindle-cell proliferations displaying prominent schwannoma-like architecture, intratumoral angiodysplasia, and entrapped native renal tubules with "onion-skin" tumor collarettes. The tumor stroma expressed CD34, estrogen, and progesterone and did not express desmin, smooth muscle actin, S-100, or TLE-1. Considering the characteristic morphology and immunophenotype, a diagnosis of "metanephric stromal tumor, cellular type," was made. This is an exceptionally rare disease manifestation in an adult patient and the first description of MST with such high stromal cellularity, making this case unique in both clinical and pathological presentation.

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Section: Introductionmentioning

confidence: 99%

Cellular Metanephric Stromal Tumor in a Postmenopausal Woman

2012

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“…MST is usually centered in the renal medulla;[79]however, in rare cases, it seemed to originate from renal cortex. [3]…”

Section: Discussionmentioning

confidence: 99%

“…Grossly, MST mainly presents as a solid nodular lesion centered in the renal medulla containing cysts[9]and rarely as a large cystic mass with a peripheral solid component. [36]…”

Section: Discussionmentioning

confidence: 99%

Metanephric stromal tumor: An unusual presentation of a rare paediatric renal neoplasm

Abdeljelil

Hadhri

Njima

et al. 2018

Afr J Paediatr Surg

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A 2-year-old boy with prenatal diagnosis of a malformation uropathy was referred to paediatric surgery department. On systemic examination, there were no palpable masses. An ultrasonography of abdomen with color Doppler, a renal artery angiographic and scintigraphy revealed a preostial aneurysm at the left renal artery. The patient had a left nephrectomy. Grossly, the specimen measured 75 mm × mm 50 × 20 mm with renal artery aneurysm measuring 30 mm × 35 mm. On cut section, the renal parenchyma contained a whitish tumor that measured 35 mm × 10 mm. Histopathologically, this tumor was diagnosed as metanephric stromal tumor.

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