Uncertainty health risk assessment and regional control of drinking water: a case study of Hanyuan County, southwest mountainous area, China

Lin, Zhengjiang; Liu, Ying; Cheng, Zhihui; Zhao, Rui; Zhang, Han

doi:10.1007/s11356-022-20688-y

Cited by 3 publications

(2 citation statements)

References 26 publications

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“…In the results of this study, no statistically significant effect of perchlorate in drinking water on height and weight at 8, 17, and 18 years of age was found, but there was a downward trend. Studies have shown that because children are sensitive ( 6 , 12 , 13 ), height and weight are more vulnerable than adults to environmental pollutants, and our findings suggest that perchlorate may be harmful to children’s height and weight. Long-term exposure to perchlorate is strongly associated with normal growth rates at different stages of adolescence ( 14 ), which may explain the different effects of perchlorate in children and adolescents of different ages in this study.…”

Section: Discussionmentioning

confidence: 48%

“…According to the World Health Organization, 80% of diseases worldwide are caused by contaminated drinking water; 50% of the deaths of children around the globe are from contaminated drinking water ( 12 ). Research has shown that the health-related quality of life of children and adolescents is affected by height and weight, and children’s height and weight are closely related to environmental pollution, especially drinking water pollution, and its impact is inseparable from human life ( 13 ).In this study, we quantified the specific effects of perchlorate in drinking water in children and adolescents at each age stage and found that the height and weight of children and adolescents had a dose–response relationship with perchlorate exposure in drinking water, decreased by the influence of perchlorate in drinking water, and had a statistically significant effect on the weight of adolescents aged 6, 7, and 11–14 years, and adolescents aged 11–15 and 18 years.…”

Section: Discussionmentioning

confidence: 99%

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The association between perchlorate in drinking water and height and weight of children and adolescents in Southwest China: a retrospective cross-sectional study

Guo,

Zong,

Yong

et al. 2023

Front. Public Health

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ObjectiveTo investigate the association between the concentration of perchlorate in drinking water and the height and weight of children and adolescents in Sichuan Province.MethodsPerchlorate in the drinking water of 24 counties in Sichuan Province from 2021 to 2022 was detected and analyzed, 66 drinking water samples were collected, and the content of perchlorate in drinking water during the wet season and dry season was detected by ultra-high performance liquid chromatography in series. The linear mixed effect model was used to estimate the relationship between perchlorate in drinking water and the height and weight of 144,644 children and adolescents, and 33 pieces of local average wage data were used as confounding factors for quality control.ResultsAfter controlling the age, gender, and local economic situation, we found that the concentration of perchlorate in drinking water increased by 10 μg/L is associated with a 1.0 cm decrease in height and a 1.6 kg decrease in weight in children and adolescents (p < 0.05).ConclusionThe concentration of perchlorate in drinking water may be negatively correlated with the height and weight of children.

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Section: Discussionmentioning

confidence: 48%

Section: Discussionmentioning

confidence: 99%

The association between perchlorate in drinking water and height and weight of children and adolescents in Southwest China: a retrospective cross-sectional study

Guo,

Zong,

Yong

et al. 2023

Front. Public Health

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Identification of water pollution sources and analysis of pollution trigger conditions in Jiuqu River, Luxian County, China

Liu,

Lin

et al. 2024

Environ Sci Pollut Res

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Chromium in Water and Carcinogenic Human Health Risk

et al. 2023

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Understanding the extent of human health risks with an emphasis on carcinogenesis development attributable to potentially toxic chemicals is critical to effective prevention and mitigation strategies. Chromium (Cr), mainly the hexavalent chromium (Cr (VI)), is a chemical associated with cancer when found in drinking water, making it a major public health issue. This study assessed a possible carcinogenic human health risk among the general population due to exposure to total or hexavalent chromium. We performed a systematic review of the international scientific literature, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol to determine the human risk of cancer mortality and morbidity. In total, 76 articles were checked for eligibility, 13 of which were included in the final systematic review. Only scientific articles from January 2000 to November 2022 published on PubMed were included. Data from both epidemiological ecological studies (Relative Risk and Rate Ratio—RR and Standardized Mortality Rate—SMR) and epidemiological case studies (Lifetime Cancer Risk—LCR, Incremental Lifetime Cancer Risk—ILCR, Cancer Risk—CR, Hazard Quotient—HQ, Hazard Index—HI, Health Risk Assessment—HRA, Disability-Adjusted Life Year—DALY, and Chronic Daily Intake Index—CDI) were included for the overall assessment of carcinogenicity in the general population. According to most articles, there is credible evidence that hexavalent chromium via water is indicated as a major contributor to the global burden of cancer in humans. Some of them emphasize malignant neoplasms in the lung, liver, stomach, and genitourinary system. Although the health index data of the case studies are based on a limited number of samples, they raise concerns about the possibility of an increase in the degree of carcinogenesis. However, there are significant limitations due to the lack of information on the dose and duration of exposure in the target group. Further research involving extensive analysis of the association of the two variables is needed, which depends on more complete information extraction and advanced methodologies.

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Uncertainty health risk assessment and regional control of drinking water: a case study of Hanyuan County, southwest mountainous area, China

Cited by 3 publications

References 26 publications

The association between perchlorate in drinking water and height and weight of children and adolescents in Southwest China: a retrospective cross-sectional study

The association between perchlorate in drinking water and height and weight of children and adolescents in Southwest China: a retrospective cross-sectional study

Identification of water pollution sources and analysis of pollution trigger conditions in Jiuqu River, Luxian County, China

Chromium in Water and Carcinogenic Human Health Risk

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