Diabetes mellitus is a chronic and often debilitating illness, and its prevalence is rapidly increasing across the globe. Though it originates in the pancreas, diabetes affects multiple organs and systems in the body, including the kidneys, eyes, nervous system, and heart. Beyond its physical effects, diabetes is also associated with depression, social isolation, and difficulty maintaining relationships. Health communication scholars have addressed both individual and relational correlates of diabetes, including self‐care, health literacy, uncertainty, coping, the patient–clinician relationship, stigma, and social support. Importantly, not all people with diabetes have similar experiences, given the healthcare inequities that exist for racially marginalized groups, people with lower socioeconomic status, and individuals in larger bodies. Health communication scholarship should continue to investigate the diabetes experience, focusing on structural inequities, the role of the media, and health communication campaigns aimed at prevention.