Uncaria tomentosa extract: evaluation of effects on the in vitro and in vivo labeling of blood constituents with technetium-99m

Abstract

The influence (in vivo and in vitro)

Influence of a Ginkgo biloba extract on the binding of [F-18]-fluorodeoxyglucose (18F-FDG) on blood constituents

“…Moreover, authors have pointed out that in nuclear medicine, it is essential the understanding and quantification of this phenomenon in order to anticipate the behavior in vivo of radiotracers (Velasques de Oliveira et al, 2010b). In addition, authors have reported that several synthetic (Nigri et al, 2002) and natural medications (Moreno et al, 2007;Moreno et al, 2008a;Moreno et al, 2008b;Moreno et al, 2008c;Souza et al, 2011) are capable of interfering with the biodistribution and/or on the radiolabeling of blood constituents. These considerations show the importance of the studies about the effect of medications on the behavior of the radiopharmaceuticals.…”