Un cas d’hémorragie cutanéomuqueuse secondaire à un déficit d’apport en vitamine K dans le syndrome d’hyperemesis gravidarum

Devignes, J.; Grare, Marion; Raft, Julien; Vial, F.; Hacquard, Marie; Lecompte, Thomas; Maistre, Emmanuel de

doi:10.1016/j.annfar.2009.05.016

Cited by 6 publications

(1 citation statement)

References 11 publications

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“…Few reports showed that maternal hemorrhage was the first manifestation in HG-related VK deficiency. Robinson et al [6] and Devignes et al [7] reported that VK-deficiency-related coagulopathy in HG caused marked maternal epistaxis and maternal skin/mucosa hemorrhage, respectively. The present report also showed that maternal hemorrhage or a hemorrhagic tendency can be the first manifestation of this condition.…”

Section: Discussionmentioning

confidence: 99%

Intraperitoneal Hemorrhage in a Pregnant Woman with Hyperemesis Gravidarum: Vitamin K Deficiency as a Possible Cause

Baba

Morisawa

Saito

et al. 2016

Case Reports in Obstetrics and Gynecology

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Hyperemesis gravidarum can cause various vitamin deficiencies. Vitamin K deficiency can lead to coagulopathy or hemorrhagic diathesis. A nulliparous Japanese woman with hyperemesis gravidarum at 105/7 weeks was admitted with giant myoma, intestinal obstruction, and abdominal pain. Treatment for a degenerative myoma was instituted with intravenous antibiotics. The abdominal pain ameliorated, but intestinal obstruction persisted. At 166/7 weeks, we performed laparotomy for release of intestinal obstruction, when intraabdominal bleeding of 110 mL existed. Blood tests revealed coagulopathy secondary to vitamin K deficiency. The coagulopathy responded to intravenous vitamin K injection. Coagulopathy due to vitamin K deficiency can occur with hyperemesis gravidarum, and coexisting intestinal obstruction and broad-spectrum antibiotics can aggravate the deficiency.

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Section: Discussionmentioning

confidence: 99%

Intraperitoneal Hemorrhage in a Pregnant Woman with Hyperemesis Gravidarum: Vitamin K Deficiency as a Possible Cause

Baba

Morisawa

Saito

et al. 2016

Case Reports in Obstetrics and Gynecology

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Maternal vitamin K deficient embryopathy: Association with hyperemesis gravidarum and Crohn disease

Toriello

Erick

Alessandri³

et al. 2013

American J of Med Genetics Pt A

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Chondrodysplasia punctata (CDP) is an etiologically heterogeneous disorder characterized by the radiographic finding of stippled epiphyses (punctate calcifications). It is often accompanied by a characteristic facial appearance, known as the Binder phenotype, which is attributed to hypoplasia of the nasal cartilages; abnormal distal phalanges (brachytelephalangy) are a common component manifestation as well. We report eight patients with a Binder phenotype with or without CDP who all shared a known or suspected maternal deficiency of vitamin K. We suspect that this phenotype is probably under recognized, and we hope to increase awareness about the maternal risk factors, especially hyperemesis gravidarum, which lead to nutritional deficiency.

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Exacerbation of a maternal hiatus hernia in early pregnancy presenting with symptoms of hyperemesis gravidarum: case report and review of the literature

Schwentner

Wulff

Herr

2010

Arch Gynecol Obstet

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Un cas d’hémorragie cutanéomuqueuse secondaire à un déficit d’apport en vitamine K dans le syndrome d’hyperemesis gravidarum

Cited by 6 publications

References 11 publications

Intraperitoneal Hemorrhage in a Pregnant Woman with Hyperemesis Gravidarum: Vitamin K Deficiency as a Possible Cause

Intraperitoneal Hemorrhage in a Pregnant Woman with Hyperemesis Gravidarum: Vitamin K Deficiency as a Possible Cause

Maternal vitamin K deficient embryopathy: Association with hyperemesis gravidarum and Crohn disease

Exacerbation of a maternal hiatus hernia in early pregnancy presenting with symptoms of hyperemesis gravidarum: case report and review of the literature

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