Umbilical metastasis (Sister Mary Joseph's nodule) in a child

Norman, Jackson T.; Wagner, Milton L.; Chintagumpala, Murali

doi:10.1007/s002470050293

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Sister Mary Joseph's nodule as presenting sign of a desmoplastic small round cell tumor

Doros

Kaste

Rodríguez‐Galindo

2006

Pediatric Blood & Cancer

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Umbilical metastases, also named Sister Mary Joseph's nodules, are well documented in the adult population and most often represent an underlying intra-abdominal malignancy, usually a carcinoma of gastrointestinal or gynecologic origin. They are indicative of widespread abdominal disease and are associated with a poor prognosis. An extensive review of the literature reveals only two such presentations in the pediatric population. A 14-year-old male presented with an umbilical mass, which was found to be a metastatic lesion of a desmoplastic small round cell tumor (DSRCT) of the abdomen. The diagnosis of an intra-abdominal malignancy, most commonly a DSRCT, should be considered in the presence of an umbilical mass in a child.

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