Umbilical cord inverting technique: a simple method to utilize the umbilical cord as a biologic dressing for sutureless gastroschisis closure

Machida, Mizuho; Takamizawa, Satoshi; Yoshizawa, Kazuya

doi:10.1007/s00383-010-2713-3

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…Even though this method seems foul-proof, one of the outcomes to look out for is the development of an umbilical hernia after complete healing, which was described in a few studies [5] , [6] , [10] , [11] particularly after cutting the rectus fascia [6] , as well as shown in our cases; though in our patients the rectus fascia was not breeched. We followed up a cohort of four patients who had umbilical cord graft without cutting of the of rectus fascia.…”

Section: Discussionsupporting

confidence: 50%

Umbilical hernia repair post umbilical cord graft closure of gastroschisis: A cohort study

Taher

Khalil

Ahmed

et al. 2022

International Journal of Surgery Case Reports

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Section: Discussionsupporting

confidence: 50%

Umbilical hernia repair post umbilical cord graft closure of gastroschisis: A cohort study

Taher

Khalil

Ahmed

et al. 2022

International Journal of Surgery Case Reports

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“…In the group operated with silo, to keep umbilical cord moist until final defect closure, we used umbilical cord inverting technique. 6 In three infants, midline defect incision was performed; in one infant before placing spring-loaded silo and in two because of the following complications. In one infant few hours after placing silo, signs of bowel ischemia appeared which is caused by compression of too big silo used in the narrow native defect.…”

Section: Resultsmentioning

confidence: 99%

“…After preserving umbilical cord, sutureless technique can be used with optimal cosmetic results. 6 Over time, tailored umbilical cord used for bridging and closing the abdominal defect is naturally absorbed and epithelialized, converting primary defect to the umbilical hernia. 16,20 Fortunately, the natural process of self-contraction of the defect continues and only little more than half of infants in our series presented umbilical hernia at discharge.…”

Section: Discussionmentioning

confidence: 99%

Cosmetic Outcomes of Sutureless Closure in Gastroschisis

et al. 2016

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A sutureless gastroschisis repair allows for spontaneous closure of abdominal wall defect. We report our experience focusing on final esthetic outcome. Retrospective data were collected from medical reports of all neonates with gastroschisis operated from January 2009 to December 2013. Variables recorded included patients descriptors, management modality, and cosmetic outcome. From the overall group of 38 patients with gastroschisis, 20 infants treated with sutureless closure were included in this study. In the analyzed cohort, 17 (85%) children were operated under general anesthesia and 3 (15%) without intubation. Primary reduction was possible in 15 (75%) cases, and in 5 (25%) we used silo. There were two (10%) deaths in late postoperative course due to septic complications. Three (15%) infants needed laparotomy because of adhesions and bowel obstruction. There were no infectious complications of the wound. Only 55% (10/18) of children presented umbilical hernia prior to discharge. Only two (11%) children with umbilical hernia were operated until now. Almost all patients (16/18; 89%) present excellent final cosmetic result without scar formation. Sutureless closure of uncomplicated gastroschisis is a safe technique that reduces need of intubation and provides excellent cosmetic results.

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“…Umbilical cord patch (UCP) has shown to improve the repair of gastroschisis defects, opening the possibility to apply it in other neonatal and adult defects and wounds (Machida et al, 2011;Liu et al, 2018). Previous research showed that the cryopreservation (Papanna et al, 2015a,b) of HUC allowed its stocking and use on demand, independently of birth events.…”

Section: Applications Of Preserved Cryogenic Hucmentioning

confidence: 99%

Use of Human Umbilical Cord and Its Byproducts in Tissue Regeneration

Velarde

Castañeda

Morales

et al. 2020

Front. Bioeng. Biotechnol.

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The fresh or cryopreserved human umbilical cord (HUC) and its byproducts, such as cells and extracts, have different uses in tissue regeneration. Defining what HUC byproduct is more effective in a particular application is a challenge. Furthermore, the methods of isolation, culture and preservation, may affect cell viability and regenerative properties. In this article, we review the HUC and its byproducts' applications in research and clinical practice. We present our results of successful use of HUC as a patch to treat gastroschisis and its potential to be applied in other conditions. Our in vitro results show an increase in proliferation and migration of human fibroblasts by using an acellular HUC extract. Our goal is to promote standardization of procedures and point out that applications of HUC and its byproducts, as well as the resulting advances in regenerative medicine, will depend on rigorous quality control and on more research in this area.

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Umbilical cord inverting technique: a simple method to utilize the umbilical cord as a biologic dressing for sutureless gastroschisis closure

Cited by 6 publications

References 6 publications

Umbilical hernia repair post umbilical cord graft closure of gastroschisis: A cohort study

Umbilical hernia repair post umbilical cord graft closure of gastroschisis: A cohort study

Cosmetic Outcomes of Sutureless Closure in Gastroschisis

Use of Human Umbilical Cord and Its Byproducts in Tissue Regeneration

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