Umbilical cord blood processing with the Optipress II blood extractor

Godinho, M.I.; Sousa, Marisa; Carvalhais, Alzira; Barbosa, I.L.

doi:10.1080/146532400539387

Cited by 11 publications

(9 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[5][6][7][8][9][10] To improve cell recovery and standardize the process, other approaches with automated or semiautomated methods have also been developed. [11][12][13] U In our CB bank, we have recently substituted the HES method by top-and-bottom fractionation with the Optipress II (Baxter Healthcare, Deerfield, IL), to simplify the process and save time. With the aim of establishing the efficacy of the new technique, we have compared the two different methods in both development and routine phases.…”

Section: Study Design and Methodsmentioning

confidence: 99%

Red blood cell depletion with a semiautomated system or hydroxyethyl starch sedimentation for routine cord blood banking: a comparative study

Solves¹,

Mirabet²,

Planelles³

et al. 2005

Transfusion

View full text Add to dashboard Cite

show abstract

Section: Study Design and Methodsmentioning

confidence: 99%

Red blood cell depletion with a semiautomated system or hydroxyethyl starch sedimentation for routine cord blood banking: a comparative study

Solves¹,

Mirabet²,

Planelles³

et al. 2005

Transfusion

View full text Add to dashboard Cite

show abstract

“…CB was centrifuged and volume reduced (Optipress II, Baxter Healthcare, IL, USA) to obtain a buffy coat, using standard procedures established for CB banking [8]. Samples from the buffy coat were removed for NC and CD34 ' count and CD34 ' viability testing.…”

Section: Cb Collectionmentioning

confidence: 99%

Novel cryoprotectant significantly improves the post-thaw recovery and quality of HSC from CB

2006

View full text Add to dashboard Cite

“…and Godinho et al. used centrifugation to deplete the buffy‐coat from the RBC [60,61]. The mean RBC loss in these studies was respectively 53% and 34% (range 5–77) in UCB units smaller than 80 ml, compared to 56% (range 32–75) in UCB units that were larger than 80 ml.…”

Section: Resultsmentioning

confidence: 99%

The use of cord blood for transfusion purposes: current status

Khodabux

Brand

2009

Vox Sanguinis

View full text Add to dashboard Cite

Although the use of umbilical cord blood (UCB) for transfusion purposes has been proposed decades ago, the employ is still limited. In this article we review studies evaluating UCB collection efficiency and sterility, examine processing and storage of UCB-derived red blood cells (RBC) and discuss clinical studies in which UCB was used for transfusion purposes. Efforts to provide preterm newborns with autologous RBC derived from UCB have not been very successful. UCB collected after full-term deliveries can however easily be processed into RBC products and could be used autologous in case surgery of the neonate is indicated early after birth, or for allogeneic small volume paediatric transfusions. To harvest enough UCB volume, immediate clamping of the umbilical cord is commonly used as standard practice. Although delayed cord clamping has shown to improve the iron status in full-term infants; for small-for-gestational-age infants this has not been demonstrated. In addition, an increased need for phototherapy after delayed clamping exists. Altogether, we could find no disencouraging evidence to collect UCB, which could be processed into an easily available RBC product for paediatric transfusion in resource-restricted countries.

show abstract

Umbilical cord blood processing with the Optipress II blood extractor

Cited by 11 publications

References 11 publications

Red blood cell depletion with a semiautomated system or hydroxyethyl starch sedimentation for routine cord blood banking: a comparative study

Red blood cell depletion with a semiautomated system or hydroxyethyl starch sedimentation for routine cord blood banking: a comparative study

Novel cryoprotectant significantly improves the post-thaw recovery and quality of HSC from CB

The use of cord blood for transfusion purposes: current status

Contact Info

Product

Resources

About