Umbilical cord anomalies: antenatal ultrasound findings and postnatal correlation

Kong, Catrin Kar Yee; Khoo, Zi Xean; Li, Fay Xiangzhen; Chandran, Suresh

doi:10.1136/bcr-2018-226651

Cited by 6 publications

(5 citation statements)

References 23 publications

(15 reference statements)

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“…In terms of investigating the presence of POMD, postnatal ultrasound is the most frequently used modality—likely because it is readily available in most hospitals and it provides a good quality image of intra-abdominal structures 1. Antenatal ultrasound diagnosis is very limited and can be challenging 55. Some cases have reported the use of a fistulogram or scintigraphy 9 56.…”

Section: Discussionmentioning

confidence: 99%

Persistent omphalomesenteric duct in an infant with trisomy 21

Aghababaie,

Ho,

Kelay

et al. 2024

BMJ Case Rep

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We present the case of a term newborn with trisomy 21 who presented to the paediatric emergency department with periumbilical flare and green-brown discharge from a clamped umbilical cord, initially suspected to be omphalitis. However, it was noticed later, that when the infant strained or cried, a thick, bubbling and offensive green-brown discharge came out of the clamped umbilical cord with umbilical flatus. An ultrasound abdomen and umbilical cord confirmed the presence of a persistent omphalomesenteric duct (POMD). He was then transferred to the paediatric surgical unit. There, he underwent a laparotomy and surgical resection of the POMD and was discharged home 2 days later.

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Section: Discussionmentioning

confidence: 99%

Persistent omphalomesenteric duct in an infant with trisomy 21

Aghababaie,

Ho,

Kelay

et al. 2024

BMJ Case Rep

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“…The prevalence of all urachal anomalies in their general pediatric population was 1.03%. True patent urachus was a rare diagnosis, representing only 1.5% of all diagnosed urachal anomalies 3 .…”

Section: Introductionmentioning

confidence: 99%

Prenatal diagnosis of patent urachus by demonstrating bi-directional flow from the bladder

PEKAR-ZLOTIN,

Zmora,

Maymon

et al. 2023

Preprint

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Patent urachus connects the urinary bladder with the umbilicus and is an intra-abdominal portion of the allantois duct. In most cases, the urachus obliterates at approximately six weeks of gestation. The prenatal diagnosis of patent urachus is rare and can lead to both maternal and physician anxiety. Here in we present a case of prenatal diagnosis of open urachus by demonstrating a bi-directional flow from the bladder to both the penis and the urachus and its outcome.

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“… 3 Although rare, umbilical cord cysts represent the second most common anomaly of the umbilical cord. 4 Umbilical cord cysts can be isolated or nonisolated ultrasound findings during the pregnancy period, and the prognosis varies with the status of multiple or unique presentation and with persistent or progressive size. 5 If no other anomaly is found, the prognosis is mostly excellent.…”

Section: Introductionmentioning

confidence: 99%

A Retrospective Cohort Analysis of the Genetic Assay Results of Foetuses with Isolated and Nonisolated Umbilical Cord Cyst

Liu¹,

Wei²,

Lu³

et al. 2022

IJGM

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Objective To analyse the risk of clinical chromosomal abnormalities in foetuses with umbilical cord cysts. Methods Data from all genetic assays that were performed as part of invasive prenatal diagnoses of umbilical cord cysts between October 2014 and June 2021 were retrospectively collected from Guangdong Women and Children Hospital. We compared the differences in genetic assay findings in isolated and nonisolated umbilical cord cyst cohorts. Results A total of 49 singleton pregnancies and 2 foetuses that were one of the cotwins in monochorionic twin pregnancies were enrolled in the cohort; 20 isolated and 31 nonisolated umbilical cord cysts were identified in the cohort. One foetus (5%, 1/20) in the isolated umbilical cord cyst group showed chromosomal abnormalities and 17p12 microduplication. Twelve cases (38.7%, 12/31) of chromosomal abnormalities, including seven cases of trisomy 18, two cases of trisomy 13 and three cases of microdeletion, were identified in the nonisolated umbilical cord cyst group. The incidences of chromosomal abnormalities between the two groups were significantly different (1/20, 5% vs 13/31, 38.7%, p =0.003). There was no relative pathological medical exome sequencing finding in the three foetuses suffering from nonisolated umbilical cord cysts whose parents chose to undergo chromosomal microarray analysis (CMA) and medical exome sequencing. Conclusion This retrospective cohort study evaluated the value of CMA in foetuses with umbilical cord cysts and suggested that copy number variants (CNVs) may be the basic genetic aetiological factors that should be considered for diagnostic evaluation. We recommended CMA as a basic genetic evaluation in cases of umbilical cord cysts, especially in nonisolated cases.

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Umbilical cord anomalies: antenatal ultrasound findings and postnatal correlation

Cited by 6 publications

References 23 publications

Persistent omphalomesenteric duct in an infant with trisomy 21

Persistent omphalomesenteric duct in an infant with trisomy 21

Prenatal diagnosis of patent urachus by demonstrating bi-directional flow from the bladder

A Retrospective Cohort Analysis of the Genetic Assay Results of Foetuses with Isolated and Nonisolated Umbilical Cord Cyst

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