Ultraweak biophoton emission imaging of transplanted bladder cancer

Amano, Toshiyasu; Kobayashi, Masaki; Devaraj, B.; Usa, Masashi; Inaba, Humio

doi:10.1007/bf00300020

Cited by 48 publications

(23 citation statements)

References 14 publications

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“…Kobayashi 85,86 Biophoton detection techniques have also been used to record ultraweak photon emission from superficially transplanted tumors. [87][88][89] Recently, a CCD camera system was used to record two-dimensional biophoton images from tumors transplanted in mice. 90 In these images, recorded biophoton emission distinguishes transplanted tumors from surrounding tissue.…”

mentioning

confidence: 99%

Biophoton Detection and Low-Intensity Light Therapy: A Potential Clinical Partnership

Tafur

Wijk

et al. 2010

Photomedicine and Laser Surgery

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Low-intensity light therapy (LILT) is showing promise in the treatment of a wide variety of medical conditions. Concurrently, our knowledge of LILT mechanisms continues to expand. We are now aware of LILT's potential to induce cellular effects through, for example, accelerated ATP production and the mitigation of oxidative stress. In clinical use, however, it is often difficult to predict patient response to LILT. It appears that cellular reduction= oxidation (redox) state may play a central role in determining sensitivity to LILT and may help explain variability in patient responsiveness. In LILT, conditions associated with elevated reactive oxygen species (ROS) production, e.g. diabetic hyperglycemia, demonstrate increased sensitivity to LILT. Consequently, assessment of tissue redox conditions in vivo may prove helpful in identifying responsive tissues. A noninvasive redox measure may be useful in advancing investigation in LILT and may one day be helpful in better identifying responsive patients. The detection of biophotons, the production of which is associated with cellular redox state and the generation of ROS, represents just such an opportunity. In this review, we will present the case for pursuing further investigation into the potential clinical partnership between biophoton detection and LILT.

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mentioning

confidence: 99%

Biophoton Detection and Low-Intensity Light Therapy: A Potential Clinical Partnership

Tafur

Wijk

et al. 2010

Photomedicine and Laser Surgery

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“…Mutagenic and carcinogenic derivatives of nitrosoguanidine-induced chromosomal aberrations in Chinese hamster cell cultures were concomitant with increase of UPE intensity [32,33]. An enhanced UPE from mice with transplanted bladder cancer was detected by a 2-dimensional photon counting system [34]. Native lipid peroxidation in a mammalian nucleus membrane phase transition was demonstrated by measurements of intrinsic UPE [35].…”

Section: Experimental Data On the Influence Of The Physiological Statmentioning

confidence: 99%

Photon Emission from Perturbed and Dying Organisms: Biomedical Perspectives

Sławiński¹

2005

Complement Med Res

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Living systems spontaneously emit ultraweak light (ultraweak photon emission, UPE) during the process of metabolic reactions associated with the normal physiological state. Stress factors and pathological states change parameters of that emission, such as intensity, yield, temporal, statistical and spectral characteristics. Thus, properties of UPE are inherently associated with and derived from biochemical and biophysical excitation processes. UPE can be considered as a holistic expression of the perturbation of the physiological state of the bio-system and may carry information on the bioenergetics, kinetics and character of biochemical and physiological processes, functioning of the regulatory feedback systems and the degree of perturbation by internal and external factors. This article presents an overview of the fundamentals of UPE and its relation to physiological processes.

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“…Since then much investigation followed, culminating in the recent and pioneering works of Popp (Popp and Beloussov 2003;Popp, Nagl 1984) and Inaba (Amano and Inaba 1995;Usa and Inaba 1996).…”

Section: Introductionmentioning

confidence: 98%

“…A further development came with the introduction of the two-dimensional photon counting system, demonstrating that biophoton emission intensity did not correlate with body temperature (Usa 1991;Amano and Inaba 1995;Cohen and Popp 2007). Later Popp installed a mobile PMT system for human biophoton research, which facilitated the scanning of human spontaneous photon emission, while the subjects were lying on a bed (Cohen and Popp 1998;Cohen and Popp 1997).…”

Section: Introductionmentioning

confidence: 99%

Effects of exercises on biophoton emission of the wrist

et al. 2007

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Using two photomultiplier tubes (PMT), we measured the biophoton emission of the left and right wrists simultaneously. The subjects performed hand-grip exercises with both hands, during the measurements. We found a slow increase of the emission rates during the exercises, rising in average from 51.6 cps (counts per second) to 72.3 cps and an immediate decrease after the ending of the exercises. Simultaneous measurement of the skin temperature near the wrist using a thermocouple showed steady increase of temperature even after the ending of the exercises. Thus we demonstrated manifestly that the biophoton has no correlation with body temperature changes. We proposed a hypothesis to account the increase of the biophoton due to muscular activity. The oxygen used by the respiratory chain is the main source of reactive oxygen species (ROS) and therefore must be one of the biophoton sources. To flesh out this hypothesis we compared our data to heart beat rates and oxygen consumption values measured while doing the same type of exercises.

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Ultraweak biophoton emission imaging of transplanted bladder cancer

Cited by 48 publications

References 14 publications

Biophoton Detection and Low-Intensity Light Therapy: A Potential Clinical Partnership

Biophoton Detection and Low-Intensity Light Therapy: A Potential Clinical Partnership

Photon Emission from Perturbed and Dying Organisms: Biomedical Perspectives

Effects of exercises on biophoton emission of the wrist

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