Ultraviolet Light as a Modulator of Melanoma Development

Walker, Graeme J.; Hacker, Elke

doi:10.5772/22928

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Methodological Considerations For Enhancing Analyses1

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2016

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“…The ongoing process of chronic sun exposure and subsequent mutations (NRAS, KIT) can cause melanoma or the presence of a BRAF mutation can push the initiated melanocyte to melanoma in the absence of chronic sun exposure. 12 In a population based study, the effect of an exposure might differ between the BRAF mutated and wild type melanoma (cancer outcome) requiring subgroup examination. Along with biomarkers, cancer subtypes can be an important aspect of biological exploration.…”

Section: Methodological Considerations For Enhancing Analysesmentioning

confidence: 99%