Ultraviolet germicidal irradiation is effective against SARS-CoV-2 in contaminated makeup powder and lipstick

Bispo-dos-Santos, Karina; Barbosa, Priscilla P; Granja, Fabiana; Martini, Matheus Cavalheiro; Oliveira, Camila Flavia Schettino; Schuck, Desirée Cigaran; Brohem, Carla Abdo; Arns, Clarice Weis; Hares, Sylvio Jorge; Sabino, Caetano P.; Proença-Módena, José Luiz

doi:10.1016/j.jpap.2021.100072

Cited by 11 publications

(8 citation statements)

References 51 publications

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“…The results were expressed as the viral plaque-forming units (PFU)/mL of the sample. The virus used in this study, with a titer of 8 × 10 6 PFU/mL, was inactivated by exposure to 7560 mJ/cm 2 of UVC (30 min) according to what has been described previously [ 34 ]. The supernatant of non-infected Vero cells, inactivated by UVC, was used as a negative control.…”

Section: Methodsmentioning

confidence: 99%

Lung Inflammation Induced by Inactivated SARS-CoV-2 in C57BL/6 Female Mice Is Controlled by Intranasal Instillation of Vitamin D

Souza

Zorzella-Pezavento

Ayupe

et al. 2023

Cells

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The COVID-19 pandemic was triggered by the coronavirus SARS-CoV-2, whose peak occurred in the years 2020 and 2021. The main target of this virus is the lung, and the infection is associated with an accentuated inflammatory process involving mainly the innate arm of the immune system. Here, we described the induction of a pulmonary inflammatory process triggered by the intranasal (IN) instillation of UV-inactivated SARS-CoV-2 in C57BL/6 female mice, and then the evaluation of the ability of vitamin D (VitD) to control this process. The assays used to estimate the severity of lung involvement included the total and differential number of cells in the bronchoalveolar lavage fluid (BALF), histopathological analysis, quantification of T cell subsets, and inflammatory mediators by RT-PCR, cytokine quantification in lung homogenates, and flow cytometric analysis of cells recovered from lung parenchyma. The IN instillation of inactivated SARS-CoV-2 triggered a pulmonary inflammatory process, consisting of various cell types and mediators, resembling the typical inflammation found in transgenic mice infected with SARS-CoV-2. This inflammatory process was significantly decreased by the IN delivery of VitD, but not by its IP administration, suggesting that this hormone could have a therapeutic potential in COVID-19 if locally applied. To our knowledge, the local delivery of VitD to downmodulate lung inflammation in COVID-19 is an original proposition.

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Section: Methodsmentioning

confidence: 99%

Lung Inflammation Induced by Inactivated SARS-CoV-2 in C57BL/6 Female Mice Is Controlled by Intranasal Instillation of Vitamin D

Souza

Zorzella-Pezavento

Ayupe

et al. 2023

Cells

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“…It is not apparent that any particular SARS‐CoV‐2 strain variant is more or less resistant 110 . Differential effects can depend on surface quality and humidity 100,103,105,106,113 . Early in the pandemic, emphasis was placed on the decontamination of N95 respirators, which were in short supply 101,104 .…”

Section: Irradiation Methodsmentioning

confidence: 99%

“… 110 Differential effects can depend on surface quality and humidity. 100 , 103 , 105 , 106 , 113 Early in the pandemic, emphasis was placed on the decontamination of N95 respirators, which were in short supply. 101 , 104 For the latter use, variable effects of UV‐C were seen on the irregular surface of these masks, but it must be acknowledged that mask layers may trap virus at different strata.…”

Section: Irradiation Methodsmentioning

confidence: 99%

Disinfection and decontamination in the context of SARS‐CoV‐2‐specific data

Cimolai

2022

Journal of Medical Virology

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Given the high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) as witnessed early in the coronavirus disease 2019 (COVID‐19) pandemic, concerns arose with the existing methods for virus disinfection and decontamination. The need for SARS‐CoV‐2‐specific data stimulated considerable research in this regard. Overall, SARS‐CoV‐2 is practically and equally susceptible to approaches for disinfection and decontamination that have been previously found for other human or animal coronaviruses. The latter have included techniques utilizing temperature modulation, pH extremes, irradiation, and chemical treatments. These physicochemical methods are a necessary adjunct to other prevention strategies, given the environmental and patient surface ubiquity of the virus. Classic studies of disinfection have also allowed for extrapolation to the eradication of the virus on human mucosal surfaces by some chemical means. Despite considerable laboratory study, practical field assessments are generally lacking and need to be encouraged to confirm the correlation of interventions with viral eradication and infection prevention. Transparency in the constitution and use of any method or chemical is also essential to furthering practical applications.

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“…To augment the black and pink areas of residual face paint (DC3), we first tried special light sources [50]. Ultra-Violet (UV) light has been widely used in skin disease diagnosis, and it is also effective in allowing cosmetic residues to fluoresce [9]. However, the eye area can be irreversibly and severely damaged by exposure to UV light [48].…”

Section: Workflow2: Timing and Visualizationmentioning

confidence: 99%

“It is hard to remove from my eye”: Design Makeup Residue Visualization System for Chinese Traditional Opera (Xiqu) Performers

Xiong,

Fu,

Zhu

et al. 2024

Proceedings of the CHI Conference on Human Factors in Computing Systems

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Chinese traditional opera (Xiqu) performers often experience skin problems due to the long-term use of heavy-metal-laden face paints. To explore the current skincare challenges encountered by Xiqu performers, we conducted an online survey (N=136) and semistructured interviews (N=15) as a formative study. We found that incomplete makeup removal is the leading cause of human-induced skin problems, especially the difficulty in removing eye makeup. Therefore, we proposed EyeVis, a prototype that can visualize the residual eye makeup and record the time make-up was worn by Xiqu performers. We conducted a 7-day deployment study (N=12) to evaluate EyeVis. Results indicate that EyeVis helps to increase Xiqu performers' awareness about removing makeup, as well as boosting their confidence and security in skincare. Overall, this work also provides implications for studying the work of people who wear makeup on a daily basis, and helps to promote and preserve the intangible cultural heritage of practitioners.CCS Concepts: • Human-centered computing → Empirical studies in HCI; Assistive technologies.

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Ultraviolet germicidal irradiation is effective against SARS-CoV-2 in contaminated makeup powder and lipstick

Cited by 11 publications

References 51 publications

Lung Inflammation Induced by Inactivated SARS-CoV-2 in C57BL/6 Female Mice Is Controlled by Intranasal Instillation of Vitamin D

Lung Inflammation Induced by Inactivated SARS-CoV-2 in C57BL/6 Female Mice Is Controlled by Intranasal Instillation of Vitamin D

Disinfection and decontamination in the context of SARS‐CoV‐2‐specific data

“It is hard to remove from my eye”: Design Makeup Residue Visualization System for Chinese Traditional Opera (Xiqu) Performers

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