Ultraviolet disinfection efficacy test method using bacteria monolayers

Kowalski, Władysław; Moeller, Ralf; Walsh, Thomas J.; Petraitis, Vidmantas; Passman, Frederick J.

doi:10.1016/j.mimet.2022.106541

Cited by 9 publications

(14 citation statements)

References 24 publications

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“…The highest level of UVI was recorded during 6-7 th April 2020 when the UVI touched ~7.3 which falls in the high-risk category. The UVI was in the moderate level (3)(4)(5) during normal period in Delhi. It is noticed that the magnitude of UVI in 2020 was significantly higher when compared with last three years.…”

Section: Resultsmentioning

confidence: 99%

“…It is caused by SARS-CoV-2 virus and has an extremely high transmission rate by droplet spray from coughing and sneezing and by a direct human to human contact 1 . The SARS-CoV-2 is not unique; but a new variant in the beta coronavirus family 2,3 . To fight the pandemic, many countries around the world implemented a lockdown.…”

Section: Introductionmentioning

confidence: 99%

“…According to 13 UVC range can inactivate many viruses and bacteria in times less than minute depending upon the dose. Ultraviolet light can be an effective measure for decontaminating surfaces that may be contaminated by the SARS-CoV-2 virus 3 . The usage of concentrated forms of UV-C radiation was on the front line in the fight against Covid-19 in China.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Is ultraviolet Radiation a Confounding Variable for COVID-19 in India?

Tikle¹,

Beig²

2022

J. ISAS

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The current global Coronavirus disease (COVID-19) became a pandemic due to its contagion nature and rapid spread throughout the world. The pandemic caused a lockdown resulting in a large decline in the level of anthropogenic emissions of tiny aerosol particles that altered the solar irradiance and decreased the quantity of aerosol, which opposes global warming. This study first demonstrates that surface ultraviolet radiation (UV) increased significantly during the lockdown period in four major Indian mega cities, whose magnitude varies based on city demography. Results shows that the correlation between the high rate of increase in Ultraviolet irradiance (UV-irradiance) on mortality and morbidity. Although there are numerous confounding factors for the pandemic, UV-irradiance could be one of the factors supporting the hypothesis that increased solar UV dose may increase rate of disinfection as radiation warps the structure of genetic material of the virus and deactivates it. Another factor which also have potential to add up increase of Vitamin D3 production per minute of exposure due to UV-irradiance resulting in an increased human immune system to fight COVID-19 more effectively. However, it is cautioned here that a high dose of direct UV exposure to humans may be fatal leading to skin damage and melanoma cancer. Hence, the harmful impact of UV-Irradiance on the human body and its application to possible disinfectant to virus deactivation should be understood in a proper perspective.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Is ultraviolet Radiation a Confounding Variable for COVID-19 in India?

Tikle¹,

Beig²

2022

J. ISAS

View full text Add to dashboard Cite

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“…In particular, recent COVID-19 has caused global infections, which brings the need for routine disinfection by residents and health services. UV irradiation has been widely applied to inactivate viruses because of its chemical reagent independence and the high photoreactivity of nucleic acids . Previous studies have focused on developing genomic and numerical models to predict the water-based UV inactivation rate constants of viruses without considering the complexity of the water environment in actual disinfection situations.…”

Section: Resultsmentioning

confidence: 99%

Preparing for the Next Pandemic: Predicting UV Inactivation of Coronaviruses with Machine Learning

Huang,

Ma,

Huangfu

et al. 2023

Environ. Sci. Technol.

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The epidemic of coronaviruses has posed significant public health concerns in the last two decades. An effective disinfection scheme is critical to preventing ambient virus infections and controlling the spread of further outbreaks. Ultraviolet (UV) irradiation has been a widely used approach to inactivating pathogenic viruses. However, no viable framework or model can accurately predict the UV inactivation of coronaviruses in aqueous solutions or on environmental surfaces, where viruses are commonly found and spread in public places. By conducting a systematic literature review to collect data covering a wide range of UV wavelengths and various subtypes of coronaviruses, including severe acute respiratory syndrome 2 (SARS-CoV-2), we developed machine learning models for predicting the UV inactivation effects of coronaviruses in aqueous solutions and on environmental surfaces, for which the optimal test performance was obtained with R2 = 0.927, RMSE = 0.565 and R2 = 0.888, RMSE = 0.439, respectively. Besides, the required UV doses at different wavelengths to inactivate the SARS-CoV-2 to 1 Log TCID50/mL titer from different initial titers were predicted for inactivation in protein-free water, saliva on the environmental surface, or the N95 respirator. Our models are instructive for eliminating the ongoing pandemic and controlling the spread of an emerging and unknown coronavirus outbreak.

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“…As is known, the number of surviving microorganisms on surfaces and in the air decreases exponentially with an increase in the dose of ultraviolet radiation. According to the review [33], the average dose that kills 90 % of corona viruses is 67 J/m 2 .…”

Section: Development Of An Open-type Disinfecting Device Using Uvc Ledsmentioning

confidence: 99%

Device for Inactivation of SARS-CoV-2 Using UVC LEDs

Дзюбенко

Arhun

Hnatov

et al. 2022

ELEKTRON ELEKTROTECH

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In connection with the COVID-19 pandemic, there is an urgent need for disinfecting devices that can be used both indoors and in transport. Currently, the most common of these devices are ultraviolet (UV) germicidal lamps. However, they have significant disadvantages, such as short service life, presence of mercury, lack of flexible control, large dimensions, etc. The paper analyzes the sources of UV radiation to find an alternative to UV lamps. Although these elements currently have low efficiency and high cost, etc., it is proposed to use UVC LEDs as a UV source. Due to the COVID-19 pandemic and the general interest in the fight against viruses, as well as the ban on the use of mercury, investments have been attracted in the development of UVC LEDs, which will make them competitive in the future compared to germicidal lamps both in cost and efficiency. The paper presents a disinfection device developed on the basis of UVC LEDs. The principle of operation is described; the control system, the drawing, and the design of the UVC LED-based disinfection device are presented. Due to the described limitations of UVC LEDs, this design can be used for disinfection of small surface areas where frequent on/off switching is required and high power is not required.

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Ultraviolet disinfection efficacy test method using bacteria monolayers

Cited by 9 publications

References 24 publications

Is ultraviolet Radiation a Confounding Variable for COVID-19 in India?

Is ultraviolet Radiation a Confounding Variable for COVID-19 in India?

Preparing for the Next Pandemic: Predicting UV Inactivation of Coronaviruses with Machine Learning

Device for Inactivation of SARS-CoV-2 Using UVC LEDs

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