Ultrathin surface coated water-soluble cobalt ferrite nanoparticles with high magnetic heating efficiency and rapid in vivo clearance

Shape‐Mediated Magnetocrystalline Anisotropy and Relaxation Controls by Cobalt Ferrite Core–Shell Heterostructures for Magnetothermal Penetration Delivery

“…Similar distribution of iron oxide and cobalt ferrite nanoparticles were reported in the literatures, [49][50][51] in which the particles could be cleared by the liver and spleen after 14 days. Furthermore, as documented, the sizes of particles less than 8-15 nm could be excreted through the kidney, [49,51] and the excellent water solubility are important in the degradation and clearance of particles. [50] In summary, the cobalt ferrite nanoparticles were degraded and excreted through the kidney.…”

Formation of Co–Au Core–Shell Nanoparticles with Thin Gold Shells and Soft Magnetic ε-Cobalt Cores Ruled by Thermodynamics and Kinetics

“…14 However, the generation of core− shell (CS) particles can overcome this challenge by protecting the ferromagnetic core (metallic Co) inside the noble-metal shell (Au), which increases the oxidation resistance and adds functional properties to the particles. 7,15−17 The formation of Co−Au CSNPs would also contribute to expanding the applicability of these particles in biomedicine, including targeted drug delivery, 18−20 magnetic therapy, 21,22 and medical diagnosis, 23 in addition to catalysis 24 and magnetic refrigeration, 25 where the Au shell enhances the biocompatibility of the structures while the magnetic properties of the ferromagnetic metallic Co are preserved. 14,26,27 applications of CSNPs necessitate a precise particle design as the crystal structures of the cores and shells, size of the cores, and thickness of the shells critically affect the particle's magnetism and optical properties.…”

“…Furthermore, combining the optical properties of Au with the magnetic properties of Co in a single nanoparticle (NP) increases the applicability of Co–Au nanoalloys in various fields. , The main challenge for using magnetic materials such as metallic Co in various applications is their high oxidation sensitivity, which gets more pronounced as the particle size decreases . However, the generation of core–shell (CS) particles can overcome this challenge by protecting the ferromagnetic core (metallic Co) inside the noble-metal shell (Au), which increases the oxidation resistance and adds functional properties to the particles. ,− The formation of Co–Au CSNPs would also contribute to expanding the applicability of these particles in biomedicine, including targeted drug delivery, − magnetic therapy, , and medical diagnosis, in addition to catalysis and magnetic refrigeration, where the Au shell enhances the biocompatibility of the structures while the magnetic properties of the ferromagnetic metallic Co are preserved. ,, However, all applications of CSNPs necessitate a precise particle design as the crystal structures of the cores and shells, size of the cores, and thickness of the shells critically affect the particle’s magnetism and optical properties. , …”

Energy‐converting biomaterials for cancer therapy: Category, efficiency, and biosafety

“…SDT could take advantage of ultrasound‐driven ROS‐ECBs to induce ROS production by cavitation effect, leading to tumor cell apoptosis (Huang et al, 2017; Wang et al, 2019). (d) CDT, as the emerging novel chemical‐driven cancer‐therapeutic modality, has shown broad promising applications and prospects in the past 5 years (Zhang et al, 2020). In CDT, chemical‐driven ROS‐ECBs are established to react with the intratumoral H + and H 2 O 2 via Fenton or Fenton‐like reaction to generate • OH against cancer (Tang et al, 2019).…”