Ultrathin angioscopic guidewire: preliminary in-vitro results

Castracane, James; Conerty, Michelle D.; Breisblatt, Warren M.

doi:10.1117/12.209128

Cited by 2 publications

(2 citation statements)

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“…3.1 Spatial resolution 3. PERFORMANCE Following production of the tubes, the four prototypes were extensively tested prior to coupling to the megapixel array.…”

Section: Intensifier Designmentioning

confidence: 99%

<title>High-resolution image intensifier development: preliminary results</title>

Castracane

Clow

Boskma³

1995

Cameras and Systems for Electronic Photography and Scientific Imaging

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4BSTRACTThe steady development of megapixel detector arrays with decreasing pixel size has improved the performance of present imaging systems. These high spatial resolution detectors have been incorporated into a variety of scientific experiments. The sensitivity of the diode arrays has allowed significant progress in instrumentation development and application. However, full application of these detectors to low light level measurements has been hampered by the lack of image intensifiers which can fully exploit the available spatial resolution of the diode arrays. Current architecture of image intensifiers allows significant room for improvement.We are involved in a project to design, develop and characterize an 1 8 mm GEN II image intensifier with improved spatial resolution. Recent advances in microchannel plate production and fiber optic architecture have been exploited to produce a series of image intensifiers. A production run of a series of tubes with reduced cathode to MCP spacing, reduced microchannel diameter and pitch, reduced MCP to phosphor screen spacing and an integral fiber optic taper has been carried out. This intensifier output will be visually examined and coupled to a megapixel array for digital characterization. The goal is to produce a significantly higher limiting spatial resolution to allow for improved measurements in scientific, commercial and military applications. First results from this production run will be discussed and compared to physical performance models.

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“…3.1 Spatial resolution 3. PERFORMANCE Following production of the tubes, the four prototypes were extensively tested prior to coupling to the megapixel array.…”

Section: Intensifier Designmentioning

confidence: 99%

<title>High-resolution image intensifier development: preliminary results</title>

Castracane

Clow

Boskma³

1995

Cameras and Systems for Electronic Photography and Scientific Imaging

Self Cite

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“…To construct a comprehensive in vivo diagnostic tool, the spectrometer must be combined with image processing techniques to perform time-dependent physiological process imaging events in real time. Current research has been hampered by the limited resolution inherent to fiber optic imaging systems, (Houlne et al 1996b, Castracance et al 1995 by low contrast between normal and abnormal tissue and by the low signal-to-noise ratio produced by tissue autofluorescence background (Hutchinson et al 1996, Chance and Alfano 1995, Grandjbakhche et al 1996, Bays et al 1996.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic fluorescence imaging of tissue selective lanthanide chelates

et al. 1998

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Endoscopic probes have been incorporated into a fluorescent imaging system for the remote quantitation of tissue selective markers. Resolution at the level of 114 line pairs/mm allows visualization of regions that are approximately 6 mm wide. Tissue selective markers, based on polyazamacrocyclic chelates of terbium increase contrast and can be quantified in tissues at the sub‐picomole level. Minimally invasive in vivo fluorescence imaging is demonstrated. The potential for application of the system to disease diagnosis and bone graft morphology quantitation is discussed.

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Ultrathin angioscopic guidewire: preliminary in-vitro results

Cited by 2 publications

References 0 publications

<title>High-resolution image intensifier development: preliminary results</title>

<title>High-resolution image intensifier development: preliminary results</title>

Endoscopic fluorescence imaging of tissue selective lanthanide chelates

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